Natural bioactive thiazole-based peptides from marine resources: structural and pharmacological aspects

R Dahiya, S Dahiya, NK Fuloria, S Kumar, R Mourya… - Marine Drugs, 2020 - mdpi.com
Peptides are distinctive biomacromolecules that demonstrate potential cytotoxicity and
diversified bioactivities against a variety of microorganisms including bacteria, mycobacteria …

Preparation and Characterization of Co-Grinded Mixtures of Aceclofenac and Neusilin US2 for Dissolution Enhancement of Aceclofenac

AH Vadher, JR Parikh, RH Parikh, AB Solanki - Aaps Pharmscitech, 2009 - Springer
The present study was carried out with a view to enhance the dissolution of poorly water-
soluble BCS-class II drug aceclofenac by co-grinding with novel porous carrier Neusilin US …

Development and characterization of enteric-coated immediate-release pellets of aceclofenac by extrusion/spheronization technique using κ-carrageenan as a …

VA Kilor, NP Sapkal, JG Awari, BD Shewale - AAPS PharmSciTech, 2010 - Springer
In the present study, an attempt was made to prepare immediate-release enteric-coated
pellets of aceclofenac, a poorly soluble nonsteroidal anti-inflammatory drug that has a …

Improved pharmacokinetics of aceclofenac immediate release tablets incorporating its inclusion complex with hydroxypropyl-β-cyclodextrin

S Dahiya, A Kaushik, K Pathak - Scientia pharmaceutica, 2015 - pmc.ncbi.nlm.nih.gov
The present investigation reports the various pharmacokinetic parameters of immediate
release aceclofenac tablets incorporating its inclusion complex with hydroxypropyl-β …

Ocular delivery of peptides and proteins

R Dahiya, S Dahiya - Drug delivery for the retina and posterior segment …, 2018 - Springer
The delivery of protein and peptide therapeutics through ocular route requires considerable
knowledge and understanding about eye's anatomy and physiology. Although this delivery …

Aceclofenac: species-dependent metabolism and newer paradigm shift from oral to non-oral delivery

G Sharma, J Singh, D Anand, M Kumar… - Current Topics in …, 2017 - ingentaconnect.com
Non-steroidal anti-inflammatory drugs (NSAIDs) are the group of drugs prescribed in various
pain related disorders and inflammatory conditions. Diclofenac (DI) is widely prescribed …

Solubility enhancement of glimperide: Development of solid dispersion by solvent melt method, characterization and dosage form development

S Kaushik, K Pathak - Pharmaceutical and Biomedical …, 2017 - publish.kne-publishing.com
The aim of the present work was to develop immediate release dosage form of the solid
dispersion of glimperide (GLIM) for potential enhancement in the bioavailability. The solid …

Sulindac solid dispersions: Development, characterization and in vivo evaluation of ulcerogenic activity in rats

YA Haggag, SA El-Gizawy, EEZ El-din… - Journal of Applied …, 2016 - japsonline.com
Sulindac is a poorly soluble nonsteroidal anti-inflammatory drug associated with
gastrointestinal intolerance as its serious side effect. This work investigated the ability of …

[HTML][HTML] Development of a validated stability-indicating HPLC-DAD method for dasabuvir and the characterization of its degradation products using LC-QToF-MS/MS

AM Junkert, BM Marson, MM Fachi… - Brazilian Journal of …, 2023 - SciELO Brasil
Abstract A stability-indicating HPLC-DAD method was developed and validated for the
simultaneous determination of dasabuvir and its degradation products in the pharmaceutical …

Development of inclusion complex based on cyclodextrin and oxazolidine derivative

RR Silva, CAC Amorim, MCA Lima… - Brazilian Journal of …, 2023 - SciELO Brasil
Oxazolidine derivatives (OxD) have been described as third-line antibiotics and antitumoral
agents. The inclusion complexes based on cyclodextrin could improve the solubility and …