Neural stem cells (NSCs) generate new neurons throughout life in the mammalian brain.
Adult-born neurons shape brain function, and endogenous NSCs could potentially be …

Adult neurogenesis in the hippocampus is a notable process due not only to its uniqueness
and potential impact on cognition but also to its localized vertical integration of different …

The dentate gyrus (DG) gates neocortical information flow to the hippocampus. Intriguingly,
the DG also produces adult-born dentate granule cells (abDGCs) throughout the lifespan …

Newborn microglia rapidly replenish the whole brain after selective elimination of most
microglia (> 99%) in adult mice. Previous studies reported that repopulated microglia were …

Adult neurogenesis plays critical roles in maintaining brain homeostasis and responding to
neurogenic insults. However, the adult mammalian spinal cord lacks an intrinsic capacity for …

Neural stem and progenitor cells (NSPCs) generate neurons throughout life in the
mammalian hippocampus. We used chronic in vivo imaging and followed genetically …

Adult neural stem/progenitor (B1) cells within the walls of the lateral ventricles generate
different types of neurons for the olfactory bulb (OB). The location of B1 cells determines the …

Hippocampal neurogenesis is important for certain forms of cognition, and failing
neurogenesis has been implicated in neuropsychiatric diseases. The neurogenic capacity of …

In the adult hippocampus, neuroprogenitor cells in the subgranular zone (SGZ) of the
dentate gyrus give rise to newborn neuroblasts. However, only a small subset of these cells …

Complete spinal cord injury (SCI) leads to cell death, interruption of axonal connections and
permanent functional impairments. In the development of SCI treatments, cell transplantation …