Transient receptor potential (TRP) channels are sensors for a variety of cellular and
environmental signals. Mammals express a total of 28 different TRP channel proteins, which …

Many ion channels have been described as mechanosensitive according to various criteria.
Most broadly defined, an ion channel is called mechanosensitive if its activity is controlled by …

The classification of neurons into distinct types reveals hierarchical taxonomic relationships
that reflect the extent of similarity between neuronal cell types. At the base of such …

Loss of pressure-induced vasoconstriction increases susceptibility to renal and cerebral
vascular injury. Favored paradigms underlying initiation of the response include transient …

Macrophages are present in many mechanically active tissues and are often subjected to
varying degrees of mechanical stimulation. Macrophages play a crucial role in resisting …

How do organisms without specialized auditory systems perceive and transduce sound? In
this issue of Neuron, Iliff et al.(2021) investigate the functional mechanism of airborne sound …

The classification of neurons into distinct types reveals hierarchical taxonomic relationships
that reflect the extent of similarity between neuronal cell types. At the base of such …

The lung is an inherently mechanosensitive organ, where cells of the airway and
parenchyma experience a range of mechanical forces throughout life including shear …

A phenomenon commonly observed across various musculoskeletal (MSK) diseases, such
as osteoarthritis (OA), fibromyalgia syndrome (FMS), and persistent post-surgical pain …

Chronic obstructive pulmonary disease (COPD) is characterized by alterations in
extracellular matrix (ECM). Fibroblasts and airway smooth muscle cells (ASM) are …