Polynucleotides encoding anti-CD20 antigen binding molecules with increased Fc receptor binding affinity and effector function

P Umana, P Brünker, CF Koller, T Suter… - US Patent …, 2016 - Google Patents
The present invention relates to nucleic acids encoding anti-CD20 antigen binding
molecules (ABMs). In particular embodiments, the present invention relates to nucleic acid …

Binding domain-immunoglobulin fusion proteins

JA Ledbetter, MS Hayden-Ledbetter - US Patent 7,754,208, 2010 - Google Patents
US7754208B2 - Binding domain-immunoglobulin fusion proteins - Google Patents
US7754208B2 - Binding domain-immunoglobulin fusion proteins - Google Patents Binding …

Binding domain-immunoglobulin fusion proteins

J Ledbetter, M Hayden-Ledbetter - US Patent App. 10/053,530, 2003 - Google Patents
C07K16/2809—Immunoglobulins [IGs], eg monoclonal or polyclonal antibodies against
material from animals or humans against receptors, cell surface antigens or cell surface …

Anti-CD3 antibodies, bispecific antigen-binding molecules that bind CD3 and CD20, and uses thereof

E Smith, NJ Papadopoulos - US Patent 9,657,102, 2017 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49304338&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Stably tethered structures of defined compositions with multiple functions or binding specificities

CH Chang, DM Goldenberg, WJ McBride… - US Patent …, 2009 - Google Patents
The present invention concerns methods and compositions for stably tethered structures of
de? ned compositions with multiple functionalities and/or binding speci? cities. Particu lar …

Binding constructs and methods for use thereof

JA Ledbetter, M Hayden-Ledbetter - US Patent 7,829,084, 2010 - Google Patents
2004-05-12 Assigned to TRUBION PHARMACEUTICALS, INC. reassignment TRUBION
PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

Binding domain-immunoglobulin fusion proteins

J Ledbetter, M Hayden-Ledbetter - US Patent App. 11/089,368, 2005 - Google Patents
The invention relates to novel binding domain-immunoglo bulin fusion proteins that feature a
binding domain for a cognate Structure Such as an antigen, a counterreceptor or the like, a …

Methods and compositions for generating bioactive assemblies of increased complexity and uses

CH Chang, DM Goldenberg, WJ McBride… - US Patent …, 2011 - Google Patents
Related US Application Data FOREIGN PATENT DOCUMENTS (60) Division of application
No. 1 1/478,021, filed on Jun. WO OO68248 11, 2000 29, 2006, now Pat. No. 7,534.866 …

Binding domain-immunoglobulin fusion proteins

JA Ledbetter, MS Hayden-Ledbetter - US Patent 8,106,161, 2012 - Google Patents
The invention relates to novel binding domain-immunoglo bulin fusion proteins that feature a
binding domain for a cognate structure Such as an antigen, a counterreceptor or the like, a …

Single chain multivalent binding proteins with effector function

PA Thompson, JA Ledbetter… - US Patent …, 2013 - Google Patents
Multivalent binding peptides, including bi-specific binding peptides, having immunoglobulin
effector function are provided, along with encoding nucleic acids, vectors and host cells as …