Sleep spindles: mechanisms and functions

LMJ Fernandez, A Lüthi - Physiological reviews, 2020 - journals.physiology.org
Sleep spindles are burstlike signals in the electroencephalogram (EEG) of the sleeping
mammalian brain and electrical surface correlates of neuronal oscillations in thalamus. As …

[HTML][HTML] About sleep's role in memory

B Rasch, J Born - Physiological reviews, 2013 - journals.physiology.org
Over more than a century of research has established the fact that sleep benefits the
retention of memory. In this review we aim to comprehensively cover the field of “sleep and …

Stepwise synaptic plasticity events drive the early phase of memory consolidation

A Goto, A Bota, K Miya, J Wang, S Tsukamoto, X Jiang… - Science, 2021 - science.org
Memories are initially encoded in the hippocampus but subsequently consolidated to the
cortex. Although synaptic plasticity is key to these processes, its precise spatiotemporal …

Oscillating circuitries in the sleeping brain

AR Adamantidis, C Gutierrez Herrera… - Nature Reviews …, 2019 - nature.com
Brain activity during sleep is characterized by circuit-specific oscillations, including slow
waves, spindles and theta waves, which are nested in thalamocortical or hippocampal …

Competing roles of slow oscillations and delta waves in memory consolidation versus forgetting

J Kim, T Gulati, K Ganguly - Cell, 2019 - cell.com
Sleep has been implicated in both memory consolidation and forgetting of experiences.
However, it is unclear what governs the balance between consolidation and forgetting. Here …

[HTML][HTML] Fast, cell-resolution, contiguous-wide two-photon imaging to reveal functional network architectures across multi-modal cortical areas

K Ota, Y Oisi, T Suzuki, M Ikeda, Y Ito, T Ito, H Uwamori… - Neuron, 2021 - cell.com
Fast and wide field-of-view imaging with single-cell resolution, high signal-to-noise ratio,
and no optical aberrations have the potential to inspire new avenues of investigations in …

REM sleep–active MCH neurons are involved in forgetting hippocampus-dependent memories

S Izawa, S Chowdhury, T Miyazaki, Y Mukai, D Ono… - Science, 2019 - science.org
The neural mechanisms underlying memory regulation during sleep are not yet fully
understood. We found that melanin concentrating hormone–producing neurons (MCH …

Sparse activity of hippocampal adult-born neurons during REM sleep is necessary for memory consolidation

D Kumar, I Koyanagi, A Carrier-Ruiz, P Vergara… - Neuron, 2020 - cell.com
The occurrence of dreaming during rapid eye movement (REM) sleep prompts interest in the
role of REM sleep in hippocampal-dependent episodic memory. Within the mammalian …

Perirhinal input to neocortical layer 1 controls learning

G Doron, JN Shin, N Takahashi, M Drüke, C Bocklisch… - Science, 2020 - science.org
INTRODUCTION Arguably one of the biggest mysteries in neuroscience is how the brain
stores long-term memories. Since the 1950s, it has been well established that long-term …

Sleep and homeostatic control of plasticity

G Lanza, LM DelRosso, R Ferri - Handbook of clinical neurology, 2022 - Elsevier
Sleep homeostasis is a complex neurobiologic phenomenon involving a number of
molecular pathways, neurotransmitter release, synaptic activity, and factors modulating …