A tutorial review of labeling methods in mass spectrometry-based quantitative proteomics

Z Wang, PK Liu, L Li - ACS Measurement Science Au, 2024 - ACS Publications
Recent advancements in mass spectrometry (MS) have revolutionized quantitative
proteomics, with multiplex isotope labeling emerging as a key strategy for enhancing …

High-throughput relative quantification of fatty acids by 12-plex isobaric labeling and microchip capillary electrophoresis-Mass spectrometry

Z Wang, M Li, S Xu, L Sun, L Li - Analytica Chimica Acta, 2024 - Elsevier
Abstract Background Fatty acids (FAs) are essential cellular components and play important
roles in various biological processes. Importantly, FAs produced by microorganisms from …

Recent Advances in Labeling‐Based Quantitative Glycomics: From High‐Throughput Quantification to Structural Elucidation

Z Wang, J Zhang, L Li - Proteomics, 2025 - Wiley Online Library
Glycosylation, a crucial posttranslational modification (PTM), plays important roles in
numerous biological processes and is linked to various diseases. Despite its significance …

Standards-Free Absolute Quantitation of Oxidizable Glycopeptides by Coulometric Mass Spectrometry

KY Chiu, Y Ai, M Tanim-AI Hassan, X Li… - Journal of the …, 2024 - ACS Publications
Currently, glycopeptide quantitation is mainly based on relative quantitation due to absolute
quantitation requiring isotope-labeled or standard glycopeptides which may not be …

12-Plex Isobaric Multiplex Labeling Reagents for Carbonyl-Containing Compound (SUGAR) Tag-Enabled High-Throughput Quantitative Glycomics

M Li, Y Feng, M Ma, L Li - Proteomics for Drug Discovery, 2024 - Springer
Glycans, which are ubiquitously distributed on most proteins and cell surfaces, are a class of
important biomolecules playing crucial roles in various biological processes such as …