Innervation: the missing link for biofabricated tissues and organs
S Das, WJ Gordián-Vélez, HC Ledebur… - NPJ Regenerative …, 2020 - nature.com
Innervation plays a pivotal role as a driver of tissue and organ development as well as a
means for their functional control and modulation. Therefore, innervation should be carefully …
means for their functional control and modulation. Therefore, innervation should be carefully …
Dysregulation of BRD4 function underlies the functional abnormalities of MeCP2 mutant neurons
Rett syndrome (RTT), mainly caused by mutations in methyl-CpG binding protein 2
(MeCP2), is one of the most prevalent intellectual disorders without effective therapies. Here …
(MeCP2), is one of the most prevalent intellectual disorders without effective therapies. Here …
Dog and human bladders have different neurogenic and nicotinic responses in inner versus outer detrusor muscle layers
The aim of this study was to investigate layer and species variations in detrusor muscle strip
responses to myogenic, neurogenic, and nicotinic, and muscarinic receptor stimulations …
responses to myogenic, neurogenic, and nicotinic, and muscarinic receptor stimulations …
Nerve transfer for restoration of lower motor neuron-lesioned bladder, urethral and anal sphincter function. Part 4: Effectiveness of the motor reinnervation
E Tiwari, DS Porreca, AS Braverman… - American Journal …, 2024 - journals.physiology.org
In pilot work, we showed that somatic nerve transfers can restore motor function in long-term
decentralized dogs. We continue to explore the effectiveness of motor reinnervation in 30 …
decentralized dogs. We continue to explore the effectiveness of motor reinnervation in 30 …
Nerve transfer for restoration of lower motor neuron-lesioned bladder, urethral, and anal sphincter function in a dog model. Part 3. nicotinic receptor characterization
Very little is known about the physiological role of nicotinic receptors in canine bladders,
although functional nicotinic receptors have been reported in bladders of many species …
although functional nicotinic receptors have been reported in bladders of many species …
Nerve transfer for restoration of lower motor neuron–lesioned bladder and urethra function: establishment of a canine model and interim pilot study results
E Tiwari, DM Salvadeo, AS Braverman… - … of Neurosurgery: Spine, 2019 - thejns.org
OBJECTIVE Previous patient surveys have shown that patients with spinal cord or cauda
equina injuries prioritize recovery of bladder function. The authors sought to determine if …
equina injuries prioritize recovery of bladder function. The authors sought to determine if …
Nerve transfer for restoration of lower motor neuron-lesioned bladder function. Part 1: attenuation of purinergic bladder smooth muscle contractions
N Frara, D Giaddui, AS Braverman… - American Journal …, 2021 - journals.physiology.org
This study determined the effect of pelvic organ decentralization and reinnervation 1 yr later
on the contribution of muscarinic and purinergic receptors to ex vivo, nerve-evoked, bladder …
on the contribution of muscarinic and purinergic receptors to ex vivo, nerve-evoked, bladder …
Bladder reinnervation by somatic nerve transfer to pelvic nerve vesical branches does not reinnervate the urethra
MF Barbe, AS Braverman, DM Salvadeo… - Neurourology and …, 2020 - Wiley Online Library
Aims We sought to determine whether somatic lumbar nerve transfer to the pelvic nerve's
anterior vesical branch after sacral decentralization for detrusor muscle reinnervation also …
anterior vesical branch after sacral decentralization for detrusor muscle reinnervation also …
Lateralization of bladder function in normal female canines
This study aimed to identify potential lateralization of bladder function. Electrical stimulation
of spinal roots or the pelvic nerve's anterior vesical branch was performed bilaterally in …
of spinal roots or the pelvic nerve's anterior vesical branch was performed bilaterally in …
Soft Silicone-Based Neural Interface to Improve Bladder Function
R Kumar - 2022 - search.proquest.com
This dissertation is aimed at developing a novel neural interface to improve bladder function.
Normal bladder function is compromised by many pathological conditions such as spinal …
Normal bladder function is compromised by many pathological conditions such as spinal …