Cardiovascular disease is a significant cause of morbidity and mortality in the developed
world. 3D imaging of the heart's structure is critical to the understanding and treatment of …

A plethora of catheter-based strategies have been developed to treat mitral valve disease.
Evolving 3-dimensional (3D) multidetector computed tomography (MDCT) technology can …

Biomechanical modeling has a wide range of applications in the medical field, including in
diagnosis, treatment planning and tissue engineering. The key to these predictive models …

Introduction: The left (LV) and right (RV) ventricles are linked biologically, hemodynamically,
and mechanically, a phenomenon known as ventricular interdependence. While LV function …

Percutaneous edge-to-edge mitral valve (MV) repair using MitraClip has been recently
established as a treatment option for patients with heart failure and functional mitral …

Hypoplastic left heart syndrome (HLHS) is a severe congenital heart defect in which the right
ventricle and associated tricuspid valve (TV) alone support the circulation. TV failure is thus …

Residual stress is thought to play a critical role in modulating stress distributions in soft
biological tissues and in maintaining the mechanobiological stress environment of cells …

Given the complexity of human left heart anatomy and valvular structures, the fluid–structure
interaction (FSI) simulation of native and prosthetic valves poses a significant challenge for …

Purpose Finite element simulations are an enticing tool to evaluate heart valve function;
however, patient-specific simulations derived from 3D echocardiography are hampered by …

Understanding cardiovascular growth and remodeling (G&R) is fundamental for designing
robust cardiovascular tissue engineering strategies, which enable synthetic or biological …