The gut–liver axis and the intersection with the microbiome

A Tripathi, J Debelius, DA Brenner, M Karin… - Nature reviews …, 2018 - nature.com
In the past decade, an exciting realization has been that diverse liver diseases—ranging
from nonalcoholic steatohepatitis, alcoholic steatohepatitis and cirrhosis to hepatocellular …

Alcohol, liver disease and the gut microbiota

JS Bajaj - Nature Reviews Gastroenterology & Hepatology, 2019 - nature.com
Alcoholic liver disease, which ranges from mild disease to alcoholic hepatitis and cirrhosis,
is a leading cause of morbidity and mortality worldwide. Alcohol intake can lead to changes …

The gut microbiome and liver cancer: mechanisms and clinical translation

LX Yu, RF Schwabe - Nature reviews Gastroenterology & hepatology, 2017 - nature.com
Hepatocellular carcinoma (HCC) is the third leading cause of worldwide cancer mortality.
HCC almost exclusively develops in patients with chronic liver disease, driven by a vicious …

Utilizing the gut microbiome in decompensated cirrhosis and acute-on-chronic liver failure

J Trebicka, P Bork, A Krag, M Arumugam - … reviews Gastroenterology & …, 2021 - nature.com
The human gut microbiome has emerged as a major player in human health and disease.
The liver, as the first organ to encounter microbial products that cross the gut epithelial …

Management of bacterial and fungal infections in cirrhosis: The MDRO challenge

J Fernández, S Piano, M Bartoletti, EQ Wey - Journal of hepatology, 2021 - Elsevier
Bacterial infections are frequent in cirrhotic patients with acute decompensation or acute-on-
chronic liver failure and can complicate the clinical course. Delayed diagnosis and …

Management of NAFLD: a stage-based approach

ME Rinella, AJ Sanyal - Nature reviews Gastroenterology & hepatology, 2016 - nature.com
NAFLD is the most prevalent form of liver disease in the USA, affecting an estimated 30% of
the population. The condition is associated with increased mortality related to cardiovascular …

[PDF][PDF] The use of rifaximin in patients with cirrhosis

P Caraceni, V Vargas, E Solà, C Alessandria… - …, 2021 - Wiley Online Library
Rifaximin is an oral nonsystemic antibiotic with minimal gastrointestinal absorption and
broad‐spectrum antibacterial activity covering both gram‐positive and gram‐negative …

Gut–liver axis: how do gut bacteria influence the liver?

PC Konturek, IA Harsch, K Konturek, M Schink… - Medical …, 2018 - mdpi.com
Chronic liver diseases are a major cause of morbidity and mortality worldwide. Recently, gut
dysbiosis was identified as an important factor in the pathogenesis of liver diseases. The …

Cirrhosis: a questioned risk factor for hepatocellular carcinoma

A Garrido, N Djouder - Trends in cancer, 2021 - cell.com
The liver is one of the major metabolic organs in the body, susceptible to injury caused by
various factors. In response to injury, sophisticated mechanisms are engaged to repair and …

The role of gut microbiota in some liver diseases: from an immunological perspective

L Wang, ZM Cao, LL Zhang, J Li, W Lv - Frontiers in immunology, 2022 - frontiersin.org
Gut microbiota is a microecosystem composed of various microorganisms. It plays an
important role in human metabolism, and its metabolites affect different tissues and organs …