Targeted delivery of drug molecules to diseased sites is a great challenge in pharmaceutical
and biomedical sciences. Fabrication of drug delivery systems (DDS) to target and/or …

The polysaccharides (PS) have been widely used as biomaterials in drug delivery, due to
their excellent biocompatibility, ease of functionalization, and intrinsic biological activities …

Injections of highly cytotoxic or immunomodulating drugs directly into the inoperable tumor is
a procedure that is increasingly applied in the clinic and uses established Pt-based drugs. It …

The tumor microenvironment (TME) is composed of cancerous, non-cancerous, stromal, and
immune cells that are surrounded by the components of the extracellular matrix (ECM) …

Background: Cancer remains a leading cause of death in companion animals. In human
medicine, liposomes and nanoparticles have been extensively investigated as drug delivery …

Glioblastoma multiforme is the most common and aggressive primary brain cancer with
only∼ 3% of patients surviving more than 3 years from diagnosis. Several mechanisms are …

Background: Cancer is a common disease in dogs, with a growing incidence related to the
age of the animal. Nanotechnology is being employed in the veterinary field in the same …

ABSTRACT Introduction: Hyaluronan (HA), a natural polysaccharide, is produced in large
amounts by the human body. Since its receptor CD44 is highly expressed in many types of …

Microencapsulation is a process where very minute droplets or particles of solid or liquid or
gas are trapped with a polymer to isolate the internal core material from external …

A carrier-based, immunogenic cell death (ICD)-eliciting platinum (IV) chemotherapeutic
agent was synthesized via complexation between an axially derivatized Pt (IV)-tocopherol …