Biologics now constitute a significant element of available medical treatments. Owing to their
clinical and commercial success, biologics are a rapidly growing class and have become a …

Microorganisms have been extensively applied as active biotherapeutic agents or drug
delivery vehicles for antitumor treatment because of their unparalleled bio-functionalities …

Abstract Poly (β‐amino ester)(abbreviated as PBAE or PAE) refers to a polymer synthesized
from an acrylate and an amine by Michael addition and has properties inherent to tertiary …

Polymers, lipids, scaffolds, microneedles, and other biomaterials are rapidly emerging as
technologies to improve the efficacy of vaccines against infectious disease and …

Introduction Gene delivery technologies are being developed for an increasing number of
biomedical applications, with delivery vehicles including viruses and non-viral materials …

Conventional antimicrobials are becoming increasingly ineffective for treating bacterial
infection due to the emergence of multi-drug resistant (MDR) pathogens. In addition, the …

It has long been thought that respiratory infections are the direct result of acquisition of
pathogenic viruses or bacteria, followed by their overgrowth, dissemination, and in some …

Prophylactic vaccines have evolved from traditional whole-cell vaccines to safer subunit
vaccines. However, subunit vaccines still face problems, such as poor immunogenicity and …

Poly (β-amino ester) s (PβAE) s are considered as the most potent alternative to viral
vectors, which has been increasingly proposed for targeting gene delivery, because of their …

Infectious diseases are severe public health events that threaten global health. Prophylactic
vaccines have been considered as the most effective strategy to train the immune system to …