Organisms maintain metabolic homeostasis through the combined functions of small-
molecule transporters and enzymes. While many metabolic components have been well …

Choline is an essential micronutrient critical for cellular and organismal homeostasis. As a
core component of phospholipids and sphingolipids, it is indispensable for membrane …

Purpose FLVCR1 encodes a solute carrier protein implicated in heme, choline, and
ethanolamine transport. Although Flvcr1−/− mice exhibit skeletal malformations and …

The ATP-binding cassette (ABC) and solute carrier (SLC) transporters play pivotal roles in
cellular transport mechanisms, influencing a wide range of physiological processes and …

Recent studies confirmed that host–gut microbiota interactions modulate disease-linked
metabolite TMA production via TMA lyase. However, microbial enzyme production …

Congenital hydrocephalus (CH), occurring in approximately 1/1,000 live births, represents
an important clinical challenge due to the limited knowledge of underlying molecular …

The distribution of sugars is crucial for plant energy, signaling, and defense mechanisms.
Sugar Transport Proteins (STPs) are Sugar Porters that mediate proton-driven cellular …

Abstract The Feline Leukemia Virus Subgroup C Receptor 1 isoform a (FLVCR1a) is a
ubiquitously expressed plasma membrane transporter, often found at elevated levels across …