Interleukin 6 as an energy allocator in muscle tissue

TM Kistner, BK Pedersen, DE Lieberman - Nature metabolism, 2022 - nature.com
Extensive research has shown that interleukin 6 (IL-6) is a multifunctional molecule that is
both proinflammatory and anti-inflammatory, depending on the context. Here, we combine …

Prosthetic joint infection

AJ Tande, R Patel - Clinical microbiology reviews, 2014 - Am Soc Microbiol
Prosthetic joint infection (PJI) is a tremendous burden for individual patients as well as the
global health care industry. While a small minority of joint arthroplasties will become …

[PDF][PDF] Obesity and inflammation: the linking mechanism and the complications

MS Ellulu, I Patimah, H Khaza'ai, A Rahmat… - Archives of medical …, 2017 - termedia.pl
Obesity is the accumulation of abnormal or excessive fat that may interfere with the
maintenance of an optimal state of health. The excess of macronutrients in the adipose …

Neurocognitive function after cardiac surgery: from phenotypes to mechanisms

M Berger, N Terrando, SK Smith… - …, 2018 - pmc.ncbi.nlm.nih.gov
For half a century, we have known that some patients experience neurocognitive dysfunction
after cardiac surgery, yet defining its incidence, course, and causes remains challenging …

Routine clinical markers of the magnitude of the systemic inflammatory response after elective operation: a systematic review

DG Watt, PG Horgan, DC McMillan - Surgery, 2015 - Elsevier
Background Operative injury to the body from all procedures causes a stereotypical cascade
of neuroendocrine, cytokine, myeloid, and acute phase responses. This response has been …

The exercise IL-6 enigma in cancer

ST Orange, J Leslie, M Ross, DA Mann… - Trends in Endocrinology …, 2023 - cell.com
Abstract Interleukin (IL)-6 elicits both anticancer and procancer effects depending on the
context, which we have termed the 'exercise IL-6 enigma'. IL-6 is released from skeletal …

Current recommendations for the diagnosis of acute and chronic PJI for hip and knee—cell counts, alpha-defensin, leukocyte esterase, next-generation sequencing

K Goswami, J Parvizi, P Maxwell Courtney - Current reviews in …, 2018 - Springer
Abstract Purpose of Review Despite significant progress in recent years, the diagnosis of
periprosthetic joint infection (PJI) remains a challenge and no gold standard test exists. A …

Interleukin-6, procalcitonin and TNF-α: markers of peri-prosthetic infection following total joint replacement

F Bottner, A Wegner, W Winkelmann… - The Journal of Bone …, 2007 - boneandjoint.org.uk
This prospective study evaluates the role of new laboratory markers in the diagnosis of deep
implant infection in 78 patients (41 men and 37 women) with a revision total knee or hip …

A minimal-incision technique in total hip arthroplasty does not improve early postoperative outcomes: a prospective, randomized, controlled trial

L Ogonda, R Wilson, P Archbold, M Lawlor… - JBJS, 2005 - journals.lww.com
Background: Minimally invasive total hip arthroplasty has stirred substantial controversy with
regard to whether it provides superior outcomes compared with total hip arthroplasty …

[PDF][PDF] Upregulation of Prostaglandin E~ 2 and Interleukins in the Central Nervous System and Peripheral Tissue during and after Surgery in Humans

A Buvanendran, JS Kroin, RA Berger… - ANESTHESIOLOGY …, 2006 - academia.edu
Background: The central and peripheral inflammatory re-sponse to surgery may influence
patient outcomes. This study examines the time course and clinical relevance of changes in …