Insulin signalling and GLUT4 trafficking in insulin resistance

J van Gerwen, AS Shun-Shion… - Biochemical Society …, 2023 - portlandpress.com
Insulin-stimulated glucose uptake into muscle and adipose tissue is vital for maintaining
whole-body glucose homeostasis. Insulin promotes glucose uptake into these tissues by …

Ectopic and visceral fat deposition in aging, obesity, and idiopathic pulmonary fibrosis: an interconnected role

X Cheng, S Jiang, B Pan, W Xie, J Meng - Lipids in Health and Disease, 2023 - Springer
Idiopathic pulmonary fibrosis (IPF) is considered an age-related disease. Age-related
changes, along with other factors such as obesity, hormonal imbalances, and various …

Proteolethargy is a pathogenic mechanism in chronic disease

A Dall'Agnese, MM Zheng, S Moreno, JM Platt… - Cell, 2025 - cell.com
The pathogenic mechanisms of many diseases are well understood at the molecular level,
but there are prevalent syndromes associated with pathogenic signaling, such as diabetes …

[HTML][HTML] Chicken GLUT4 function via enhancing mitochondrial oxidative phosphorylation and inhibiting ribosome pathway in skeletal muscle satellite cells

L Zhang, P Luo, H Li, Y Pan, H Zhang, X Si, W Chen… - Poultry Science, 2024 - Elsevier
ABSTRACT Glucose Transporter 4 (GLUT4) is a crucial protein facilitating glucose uptake
and metabolism across cell membranes in mammals. However, information on GLUT4 in …

Nitric oxide in modulating oxidative stress mediated skeletal muscle insulin resistance

A Anwar, S Shukla, P Pathak - Molecular Biology Reports, 2024 - Springer
Insulin resistance (IR) being the major cause behind different metabolic disorders, has
attracted a lot of attention. Epidemiological data shows marked rise in the cases over a …

Physical exercise induces increased translocation of type 4 glucose transporters (GLUT4): a systematic review

N Ayubi, JC Wibawa, HS Lesmana… - … en educación física …, 2024 - dialnet.unirioja.es
El propósito de este estudio es resaltar el impacto del ejercicio en el aumento de la
translocación de GLUT4 en las membranas celulares. Este estudio busca en muchas bases …

[HTML][HTML] Matrix mechanics regulates muscle regeneration by modulating kinesin-1 activity

WY Chiang, HW Yu, MC Wu, YM Huang, YQ Chen… - Biomaterials, 2024 - Elsevier
Sarcopenia, a prevalent muscle disease characterized by muscle mass and strength
reduction, is associated with impaired skeletal muscle regeneration. However, the influence …

[HTML][HTML] A peptide derived from the amino terminus of leptin improves glucose metabolism and energy homeostasis in myotubes and db/db mice

M Ali, A Gupta, RD Verma, S Akhtar… - Journal of Biological …, 2024 - Elsevier
Leptin is an adipokine, which plays key roles in regulation of glucose metabolism and
energy homeostasis. Therefore, identification of a short peptide from leptin which improves …

Sphingolipid metabolites as potential circulating biomarkers for sarcopenia in men

JH Seo, JM Koh, HJ Cho, H Kim, YS Lee… - Journal of Cachexia …, 2024 - Wiley Online Library
Background Sarcopenia is an age‐related progressive loss of muscle mass and function.
Sarcopenia is a multifactorial disorder, including metabolic disturbance; therefore …

Association of relative handgrip strength on the development of diabetes mellitus in elderly Koreans

YJ Sohn, HS Lee, H Bae, HC Kang, H Chun, I Ryou… - Plos one, 2024 - journals.plos.org
Background Diabetes mellitus (DM) is a significant public health concern, particularly in the
elderly population. Absolute handgrip strength (HGS) serves to quantify muscle strength. It is …