Vitiligo: a comprehensive overview: part I. Introduction, epidemiology, quality of life, diagnosis, differential diagnosis, associations, histopathology, etiology, and work …

A Alikhan, LM Felsten, M Daly… - Journal of the American …, 2011 - Elsevier
Vitiligo is an acquired pigmentary disorder of unknown etiology that is clinically
characterized by the development of white macules related to the selective loss of …

Vitiligo, reactive oxygen species and T-cells

SJ Glassman - Clinical Science, 2011 - portlandpress.com
The acquired depigmenting disorder of vitiligo affects an estimated 1% of the world
population and constitutes one of the commonest dermatoses. Although essentially …

Autoimmunity as an aetiological factor in vitiligo

N Rezaei, NG Gavalas, AP Weetman… - Journal of the …, 2007 - Wiley Online Library
Vitiligo is a common dermatological disorder characterized by the presence on the skin of
depigmented macules resulting from the destruction of cutaneous melanocytes …

Vitiligo puzzle: the pieces fall in place

W Westerhof, M d'Ischia - Pigment Cell Research, 2007 - Wiley Online Library
Over the years, the role of biochemical, immunological, genetic, and other biological aspects
in the pathogenesis of vitiligo has been studied. So far, no convincing model describing the …

The genetics of generalized vitiligo and associated autoimmune diseases

RA Spritz - Pigment Cell Research, 2007 - Wiley Online Library
Vitiligo is an acquired disorder in which patches of depigmented skin and often overlying
hair, and mucous membranes, are the result of progressive autoimmune loss of melanocytes …

[HTML][HTML] Comprehensive association analysis of candidate genes for generalized vitiligo supports XBP1, FOXP3, and TSLP

SA Birlea, Y Jin, DC Bennett, DM Herbstman… - Journal of investigative …, 2011 - Elsevier
We previously carried out a genome-wide association study of generalized vitiligo (GV) in
non-Hispanic whites, identifying 13 confirmed susceptibility loci. In this study, we re …

The genetics of generalized vitiligo

RA Spritz - Dermatologic immunity, 2008 - karger.com
Generalized vitiligo is an acquired disorder in which patches of depigmented skin, overlying
hair and oral mucosa result from progressive autoimmune loss of melanocytes from the …

The genetic concept of vitiligo

XJ Zhang, JJ Chen, JB Liu - Journal of Dermatological Science, 2005 - Elsevier
Vitiligo is a relatively common, acquired pigmentary disorder characterized by areas of
depigmented skin resulting from loss of epidermal melanocytes. The prevalence of this …

Modern vitiligo genetics sheds new light on an ancient disease

RA Spritz - The Journal of dermatology, 2013 - Wiley Online Library
Vitiligo is a complex disorder in which autoimmune destruction of melanocytes results in
white patches of skin and overlying hair. Over the past several years, extensive genetic …

LMP2-specific inhibitors: chemical genetic tools for proteasome biology

YKA Ho, P Bargagna-Mohan, M Wehenkel, R Mohan… - Chemistry & biology, 2007 - cell.com
The immunoproteasome, having been linked to neurodegenerative diseases and
hematological cancers, has been shown to play an important role in MHC class I antigen …