Ring-closing metathesis (RCM) of dienes is one of the most important methodologies now in
use for the assembly of cyclic organic compounds. First employed by Villemin and by Tsuji …

Unlike other variants of transition‐metal‐catalyzed cross‐coupling reactions, those based on
organosilicon donors have not been used extensively in natural product synthesis. However …

A novel chelated ruthenium-based metathesis catalyst bearing an N-2, 6-diisopropylphenyl
group is reported and displays near-perfect selectivity for the Z-olefin (> 95%), as well as …

Medium-sized rings are important structural units, but their synthesis, especially in a highly
enantioselective manner, has been a great challenge. Herein we report an enantioselective …

Prins‐type macrocyclizations have recently emerged as a successful strategy in the
synthesis of polyketide‐derived natural products. This reaction provides a concise and …

The first report of Z-selective macrocyclizations using a ruthenium-based metathesis catalyst
is described. The selectivity for Z macrocycles is consistently high for a diverse set of …

1. INTRODUCTION Transition-metal-catalyzed carbon− carbon-bond formations have been
one of the most intensively studied subjects in organic synthesis. 1 Among these reactions …

Asymmetric synthesis of indole-annulated medium-sized-ring compounds is developed
through an iridium-catalyzed allylic dearomatization/retro-Mannich/hydrolysis cascade …

The advent of template-directed synthesis has provided access to a range of new
interlocked molecular architectures. Although many syntheses of molecular catenanes and …

The synthesis of [2] catenanes by single macrocyclization and double macrocyclization
strategies using Cu (I) ions to catalyze covalent bond formation while simultaneously acting …