A systematic review of the protective effects of silymarin/silibinin against doxorubicin-induced cardiotoxicity

M Singh, MM Kadhim, A Turki Jalil, SK Oudah… - Cancer Cell …, 2023 - Springer
Purpose Although doxorubicin chemotherapy is commonly applied for treating different
malignant tumors, cardiotoxicity induced by this chemotherapeutic agent restricts its clinical …

Regulated cell death pathways in doxorubicin-induced cardiotoxicity

E Christidi, LR Brunham - Cell Death & Disease, 2021 - nature.com
Doxorubicin is a chemotherapeutic drug used for the treatment of various malignancies;
however, patients can experience cardiotoxic effects and this has limited the use of this …

[HTML][HTML] Oxidative stress, insulin resistance, dyslipidemia and type 2 diabetes mellitus

S Tangvarasittichai - World journal of diabetes, 2015 - ncbi.nlm.nih.gov
Oxidative stress is increased in metabolic syndrome and type 2 diabetes mellitus (T2DM)
and this appears to underlie the development of cardiovascular disease, T2DM and diabetic …

The beneficial role of curcumin on inflammation, diabetes and neurodegenerative disease: A recent update

S Ghosh, S Banerjee, PC Sil - Food and Chemical Toxicology, 2015 - Elsevier
The concept of using phytochemicals has ushered in a new revolution in pharmaceuticals.
Naturally occurring polyphenols (like curcumin, morin, resveratrol, etc.) have gained …

Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis

K Sinha, J Das, PB Pal, PC Sil - Archives of toxicology, 2013 - Springer
Oxidative stress basically defines a condition in which prooxidant–antioxidant balance in the
cell is disturbed; cellular biomolecules undergo severe oxidative damage, ultimately …

Taurine as a natural antioxidant: From direct antioxidant effects to protective action in various toxicological models

PF Surai, K Earle-Payne, MT Kidd - Antioxidants, 2021 - mdpi.com
Natural antioxidants have received tremendous attention over the last 3 decades. At the
same time, the attitude to free radicals is slowly changing, and their signalling role in …

The role of oxidative stress in cardiovascular aging and cardiovascular diseases

C Izzo, P Vitillo, P Di Pietro, V Visco, A Strianese… - Life, 2021 - mdpi.com
Aging can be seen as process characterized by accumulation of oxidative stress induced
damage. Oxidative stress derives from different endogenous and exogenous processes, all …

Taurine is involved in energy metabolism in muscles, adipose tissue, and the liver

C Wen, F Li, L Zhang, Y Duan, Q Guo… - Molecular nutrition & …, 2019 - Wiley Online Library
Energy metabolism is a basic and general process, by which the body acquires and uses
energy to maintain normal function, and taurine plays a vital role in energy metabolism …

Mechanisms of cardiac repair and regeneration

KM Broughton, BJ Wang, F Firouzi, F Khalafalla… - Circulation …, 2018 - Am Heart Assoc
Cardiovascular regenerative therapies are pursued on both basic and translational levels.
Although efficacy and value of cell therapy for myocardial regeneration can be debated …

Matrix metalloproteinase: An upcoming therapeutic approach for idiopathic pulmonary fibrosis

S Mahalanobish, S Saha, S Dutta, PC Sil - Pharmacological Research, 2020 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a debilitating condition where excess collagen
deposition occurs in the extracellular matrix. At first sight, it is expected that the level of …