Maslinic acid, a natural triterpene from Olea europaea L., induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway

FJ Reyes-Zurita, EE Rufino-Palomares, JA Lupiáñez… - Cancer letters, 2009 - Elsevier
We have investigated the mechanisms of maslinic acid with regard to its inhibitory effects on
the growth of HT29 colon-cancer cells. High concentrations of maslinic acid are present in …

Antioxidant, antiproliferative, and pro-apoptotic capacities of pentacyclic triterpenes found in the skin of olives on MCF-7 human breast cancer cells and their effects on …

Y Allouche, F Warleta, M Campos… - Journal of agricultural …, 2011 - ACS Publications
This research aimed to investigate erythrodiol, uvaol, oleanolic acid, and maslinic acid
scavenging capacities and their effects on cytotoxicity, cell proliferation, cell cycle, apoptosis …

Antiproliferative and apoptosis-inducing effects of maslinic and oleanolic acids, two pentacyclic triterpenes from olives, on HT-29 colon cancer cells

ME Juan, JM Planas, V Ruiz-Gutierrez… - British Journal of …, 2008 - cambridge.org
We have previously reported the anticarcinogenic effects of an olive fruit extract composed
of pentacyclic triterpenes, the main components of which are maslinic acid (73· 25%) and …

Extraction of interesting organic compounds from olive oil waste

J Fernández-Bolaños, G Rodríguez… - Grasas y …, 2006 - grasasyaceites.revistas.csic.es
In the olive fruits there is a large amount of bioactive compounds and substances of high
interest. Many of them are known by owing health beneficial properties that contribute to …

Modulation of cytokine secretion by pentacyclic triterpenes from olive pomace oil in human mononuclear cells

A Marquez-Martin, R De La Puerta, A Fernandez-Arche… - Cytokine, 2006 - Elsevier
Olive pomace oil, also known as “orujo” olive oil, is a blend of refined-pomace oil and virgin
olive oil, fit for human consumption. Maslinic acid, oleanolic acid, erythrodiol, and uvaol are …

Novel oleanolic and maslinic acid derivatives as a promising treatment against bacterial biofilm in nosocomial infections: an in vitro and in vivo study

N Blanco-Cabra, K Vega-Granados… - ACS Infectious …, 2019 - ACS Publications
Oleanolic acid (OA) and maslinic acid (MA) are pentacyclic triterpenic compounds that
abound in industrial olive oil waste. These compounds have renowned antimicrobial …

Supressive effect of maslinic acid from pomace olive oil on oxidative stress and cytokine production in stimulated murine macrophages

A Márquez Martín, R De La Puerta Vázquez… - Free radical …, 2006 - Taylor & Francis
The pentacyclic triterpene maslinic acid (MA) is a natural compound present in the non
glyceride fraction of pomace olive oil, also called orujo olive oil. This compound has …

[图书][B] Olive oil: minor constituents and health

D Boskou - 2008 - taylorfrancis.com
Epidemiological studies indicate that the consumption of natural antioxidants from such
plant-derived sources as olive oil produces beneficial health effects. Olive Oil: Minor …

Triterpenic compounds from “orujo” olive oil elicit vasorelaxation in aorta from spontaneously hypertensive rats

R Rodriguez-Rodriguez, JS Perona… - Journal of Agricultural …, 2006 - ACS Publications
There is currently a considerable amount of interest in the benefits of certain dietary
elements, and in particular of olive oil, in endothelial function and thus in …

Maslinic acid, a natural triterpene, induces a death receptor-mediated apoptotic mechanism in Caco-2 p53-deficient colon adenocarcinoma cells

FJ Reyes-Zurita, EE Rufino-Palomares… - PLoS …, 2016 - journals.plos.org
Maslinic acid (MA) is a natural triterpene present in high concentrations in the waxy skin of
olives. We have previously reported that MA induces apoptotic cell death via the …