Background: Debates persist on the appropriate time horizon from a payer's perspective and
how the time horizon in cost-effectiveness analysis (CEA) influences the value assessment …

The United States witnessed a nearly 4‐fold increase in personal health care expenditures
between 1980 and 2010. Despite innovations and obvious benefits to health, participants …

Abstract The ESRD Prospective Payment System introduced two incentives to increase
home dialysis use: bundling injectable medications into a single payment for treatment and …

Abstract Background With some Medicaid state programs still restricting patient access to
hepatitis C (HCV) treatment, it is important to demonstrate how states could expand …

ABSTRACT OBJECTIVES: Many therapies have immediate costs but delayed benefits.
Recent and anticipated transformative therapies may exacerbate these challenges. This …

In this article the problem of discoverability and abductive creativity in scientific cognition will
be characterized by the analysis of current difficulties that affect various aspects of the …

Doing Violence to the Production of Scientific Knowledge Page 1 Chapter 8 Doing Violence to
the Production of Scientific Knowledge Impoverishing Epistemic Niches In this chapter I will …

Today, one of the most important global public health challenges is represented by hepatitis
C virus (HCV), which imposes relevant costs. Globally speaking, the median cost of HCV …

La incorporación de los antivirales de acción directa al tratamiento de la hepatitis C crónica
permite simplificar el diagnóstico y seguimiento del paciente, optimizando los recursos …

In this chapter I will analyze some important aspects of the organization of Research and
Development (R&D) in the case of biopharmaceutical companies, which represent a …