Indole-containing small molecules have been reported to have diverse pharmacological
activities. The aromatic heterocyclic scaffold, which resembles various protein structures …

The COVID-19 pandemic has posed a significant threat to society in recent times,
endangering human health, life, and economic well-being. The disease quickly spreads due …

A series of N-benzyl substituted indole-based thiosemicarbazone (TSC) ligands (L4-L6) and
palladium (II) TSC complexes,[Pd (L) 2](1–6)(L= monoanionic bidentate un/N-substituted …

Indole thiosemicarbazones (TSCs) and their complexes are known to possess various
biological activities. The variation in anticancer activity with different indole-N substituents of …

Based on the existing reports on the bioactive isatin derivatives, a number of Schiff bases
were synthesized by reacting 5-substituted isatins with bioactive amines/hydrazides and …

Developing new anti-tyrosinase drugs seems crucial for the medical and industrial fields
since irregular melanin synthesis is linked to the resurgence of several skin conditions …

Based on the structural elements of bioactive 3-substituted indoles, a new series of indole–
thiosemicarbazone hybrid derivatives were designed, synthesized, and well-characterized …

Antibiotic resistance is becoming a cause of serious concern to human health causing a
significant impact on the global economy. The demand for novel antimicrobial agents is …

The structure assignment and conformational analysis of the thiosemicarbazones, DKI21
and DKI24, were performed through homonuclear and heteronuclear 2D Nuclear Magnetic …

ABSTRACT A series of 3-[(4-aryl-2-thiazolyl) hydrazone]-1H-indol-2, 3-dione derivatives
(2af) were designed and synthesized using isatin as starting material. The obtained thiazole …