Solid-state and biological nanopore for real-time sensing of single chemical and sequencing of DNA
Sensitivity and specificity are two most important factors to take into account for molecule
sensing, chemical detection and disease diagnosis. A perfect sensitivity is to reach the level …
sensing, chemical detection and disease diagnosis. A perfect sensitivity is to reach the level …
Engineering of protein nanopores for sequencing, chemical or protein sensing and disease diagnosis
S Wang, Z Zhao, F Haque, P Guo - Current opinion in biotechnology, 2018 - Elsevier
Highlights•Nanopore offers single molecule detection with high specificity and
sensitivity.•Protein pores have emerged as a versatile platform for single molecule …
sensitivity.•Protein pores have emerged as a versatile platform for single molecule …
Highly sensitive and selective DNA-based detection of mercury (II) with α-hemolysin nanopore
The duplex formation mediated by Hg2+ in a properly designed ssDNA generates a stable
hairpin structure, which greatly alters the translocation profile of the ssDNA through α …
hairpin structure, which greatly alters the translocation profile of the ssDNA through α …
Engineered nanopore of Phi29 DNA-packaging motor for real-time detection of single colon cancer specific antibody in serum
The ingenious design of the bacterial virus phi29 DNA packaging nanomotor with an
elegant and elaborate channel has inspired its application for single molecule detection of …
elegant and elaborate channel has inspired its application for single molecule detection of …
Portal protein: the orchestrator of capsid assembly for the dsDNA tailed bacteriophages and herpesviruses
CL Dedeo, G Cingolani… - Annual review of virology, 2019 - annualreviews.org
Tailed, double-stranded DNA bacteriophages provide a well-characterized model system for
the study of viral assembly, especially for herpesviruses and adenoviruses. A wealth of …
the study of viral assembly, especially for herpesviruses and adenoviruses. A wealth of …
Biological nanomotors with a revolution, linear, or rotation motion mechanism
The ubiquitous biological nanomotors were classified into two categories in the past: linear
and rotation motors. In 2013, a third type of biomotor, revolution without rotation …
and rotation motors. In 2013, a third type of biomotor, revolution without rotation …
Biological nanopores for sensing applications
M Zhang, C Chen, Y Zhang… - … : Structure, Function, and …, 2022 - Wiley Online Library
Biological nanopores are proteins with transmembrane pore that can be embedded in lipid
bilayer. With the development of single‐channel current measurement technologies …
bilayer. With the development of single‐channel current measurement technologies …
Real-time sensing and discrimination of single chemicals using the channel of phi29 DNA packaging nanomotor
F Haque, J Lunn, H Fang, D Smithrud, P Guo - ACS nano, 2012 - ACS Publications
A highly sensitive and reliable method to sense and identify a single chemical at extremely
low concentrations and high contamination is important for environmental surveillance …
low concentrations and high contamination is important for environmental surveillance …
[HTML][HTML] Nipple fluid for breast cancer diagnosis using the nanopore of Phi29 DNA-packaging motor
Detection of cancer in its early stage is a challenging task for oncologists. Inflammatory
breast cancer has symptoms that are similar to mastitis and can be mistaken for microbial …
breast cancer has symptoms that are similar to mastitis and can be mistaken for microbial …
Analysis with biological nanopore: On-pore, off-pore strategies and application in biological fluids
Inspired from ion channels in biology, nanopores have been developed as promising
analytical tools. In principle, nanopores provide crucial information from the observation and …
analytical tools. In principle, nanopores provide crucial information from the observation and …