Neuropsychiatric conditions including depression, anxiety disorders, and cognitive
impairment are prevalent in patients with chronic kidney disease (CKD). These conditions …

Chronic kidney disease (CKD) is considered a model of accelerated aging. More
specifically, CKD leads to reduced physical functioning and increased frailty, increased …

Abstract The Rotterdam Study is an ongoing prospective cohort study that started in 1990 in
the city of Rotterdam, The Netherlands. The study aims to unravel etiology, preclinical …

Abstract The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of
Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic …

Imaging plays an essential role in research on neurological diseases in the elderly. The
Rotterdam Scan Study was initiated as part of the ongoing Rotterdam Study with the aim to …

Rationale & Objective Chronic kidney disease (CKD) is a risk factor for cognitive decline, but
evidence is limited on its etiology and morphological manifestation in the brain. We …

Chronic kidney disease (CKD) affects more than 37 million American adults. Adult-onset
CKD is typically attributed to acquired comorbidities such as aging, type II diabetes, and …

Background: Chronic kidney disease (CKD) studies have reported variable prevalence of
brain pathologies, in part due to low inclusion of participants with moderate to severe CKD …

Objectives Thyroid dysfunction has been associated with kidney function decline, but mainly
in cross-sectional studies. Therefore, we aimed to determine the association between …

Background Relationships between early kidney disease, neurocognitive function, and brain
anatomy are poorly defined in African Americans with type 2 diabetes mellitus (T2DM) …