The focus of this article is to review the recent advances in proteome analysis of human
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …

Globally, up to approximately 800,000 new cases of hepatocellular carcinoma (HCC) are
diagnosed annually. 1, 2 The incidence of cirrhosis-related HCC is rising in the United …

We applied our'clinical glycomics' technology, based on DNA sequencer/fragment
analyzers, to generate profiles of serum protein N-glycans of liver disease patients. This …

Purpose: Proteomic profiling using surface enhanced laser desorption/ionization time of
flight mass spectrometry (SELDI-TOF MS) enables the identification of biomarkers for …

Background: Protein expression profiling for differences indicative of early cancer has
promise for improving diagnostics. This report describes the first stage of a National Cancer …

Objective: Pathological changes in an organ or tissue may be reflected in proteomic patterns
in serum. It is possible that unique serum proteomic patterns could be used to discriminate …

Colorectal cancer (CRC) is often diagnosed at a late stage with concomitant poor prognosis.
Early detection greatly improves prognosis; however, the invasive, unpleasant and …

Hepatocellular carcinoma (HCC) is a highly malignant tumor, and chronic infection with
hepatitis B virus is one of its major risk factors. To identify the proteins involved in HCC …

Purpose: Each year in the United States,∼ 30,000 people die from pancreatic cancer. Fewer
than 5% of patients survive> 5 years after diagnosis, because most patients present with …

The discovery of biomarkers is currently attracting much interest as it harbors great potential
for the diagnosis and monitoring of human diseases. Here we have used two advanced …