Metabolomics highlights pharmacological bioactivity and biochemical mechanism of traditional Chinese medicine

M Wang, L Chen, D Liu, H Chen, DD Tang… - Chemico-Biological …, 2017 - Elsevier
Traditional Chinese medicine (TCM) has attracted increasing interest throughout the world
because of its potential complementary therapy and an abundant source for new drug …

Extracting information and enhancing the quality of separation data: a review on chemometrics-assisted analysis of volatile, soluble and colloidal samples

A Zappi, V Marassi, S Giordani, N Kassouf, B Roda… - Chemosensors, 2023 - mdpi.com
Instrument automation, technological advancements and improved computational power
made separation science an extremely data-rich approach, requiring the use of statistical …

Biomass smoke inhalation promotes neuroinflammatory and metabolomic temporal changes in the hippocampus of female mice

D Scieszka, Y Jin, S Noor, E Barr, M Garcia… - Journal of …, 2023 - Springer
Smoke from wildland fires has been shown to produce neuroinflammation in preclinical
models, characterized by neural infiltrations of neutrophils and monocytes, as well as altered …

Globally optimized targeted mass spectrometry: reliable metabolomics analysis with broad coverage

H Gu, P Zhang, J Zhu, D Raftery - Analytical chemistry, 2015 - ACS Publications
Targeted detection is one of the most important methods in mass spectrometry (MS)-based
metabolomics; however, its major limitation is the reduced metabolome coverage that results …

Metabolomics and its application to the evaluation of the efficacy and toxicity of traditional Chinese herb medicines

J Shi, B Cao, XW Wang, JY Aa, JA Duan, XX Zhu… - … of Chromatography B, 2016 - Elsevier
Abstract Traditional Chinese herb medicines (TCHMs) have been used in the treatment of a
variety of diseases for thousands of years in Asian countries. The active components of …

Chemometrics applied to quality control and metabolomics for traditional Chinese medicines

S Liu, YZ Liang, H Liu - Journal of chromatography B, 2016 - Elsevier
Abstract Traditional Chinese medicines (TCMs) bring a great challenge in quality control
and evaluating the efficacy because of their complexity of chemical composition …

Polysaccharides from fermented Asparagus officinalis with Lactobacillus plantarum NCU116 alleviated liver injury via modulation of glutathione homeostasis, bile acid …

Z Zhang, S Fan, D Huang, T Xiong, S Nie, M Xie - Food & function, 2020 - pubs.rsc.org
Lactic acid bacteria strain (LAB) NCU116 fermented Asparagus officinalis polysaccharides
(FAOP) have been proven to cause substantial changes in physicochemical properties such …

Investigation on spectrum-effect correlation between constituents absorbed into blood and bioactivities of baizhu shaoyao san before and after processing on …

H Cai, Y Xu, L Xie, Y Duan, J Zhou, J Liu, M Niu… - Molecules, 2019 - mdpi.com
Baizhu Shaoyao San (BSS) is a crucial traditional Chinese medicinal formula widely applied
for the treatment of painful diarrhea, diarrhea-predominant irritable bowel syndrome …

New insights into the tonifying kidney-yin herbs and formulas for the treatment of osteoporosis

JB He, MH Chen, DK Lin - Archives of osteoporosis, 2017 - Springer
Osteoporosis is characterized by an increasing osseous fragility and fracture resulting from
the low mass and deteriorated microarchitecture in the bone tissue. The hormone …

Gut microbiome remodeling and metabolomic profile improves in response to protein pacing with intermittent fasting versus continuous caloric restriction

AE Mohr, KL Sweazea, DA Bowes, P Jasbi… - Nature …, 2024 - nature.com
The gut microbiome (GM) modulates body weight/composition and gastrointestinal
functioning; therefore, approaches targeting resident gut microbes have attracted …