Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …

Since cancer stem cells (CSCs) were first identified in leukemia in 1994, they have been
considered promising therapeutic targets for cancer therapy. These cells have self-renewal …

The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …

Cancer stem cells (CSCs), also known as tumor‐initiating cells (TICs), are suggested to be
responsible for drug resistance and cancer relapse due in part to their ability to self‐renew …

Therapeutic resistance and metastatic progression are responsible for the majority of cancer
mortalities. In particular, the development of resistance is a significant barrier to the efficacy …

Lung cancer causes the largest number of cancer-related deaths in the world. Most (85%) of
lung cancers are classified as non-small-cell lung cancer (NSCLC) and small-cell lung …

Radiation therapy is one of the major tools of cancer treatment, and is widely used for a
variety of malignant tumours. Radiotherapy causes DNA damage directly by ionization or …

Non-small-cell lung cancers (NSCLCs), the most common lung cancers, are known to have
diverse pathological features. During the past decade, in-depth analyses of lung cancer …

The human genome contains 19 putatively functional aldehyde dehydrogenase (ALDH)
genes, which encode enzymes critical for detoxification of endogenous and exogenous …

Cancer stem cells (CSC) possess abilities generally associated with embryonic or adult
stem cells, especially self-renewal and differentiation. The CSC model assumes that this …