Current and emerging treatment options for endometriosis

S Ferrero, G Evangelisti, F Barra - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Pharmacotherapy has a pivotal role in the management of endometriosis with
long-term treatments balancing clinical efficacy (control of pain symptoms and prevention of …

[HTML][HTML] Endometriosis: where are we and where are we going?

AD Greene, SA Lang, JA Kendziorski… - Reproduction …, 2016 - ncbi.nlm.nih.gov
Endometriosis currently affects∼ 5.5 million reproductive-aged women in the US with
symptoms such as painful periods (dysmenorrhea), chronic pelvic pain, pain with …

Use of dienogest in endometriosis: a narrative literature review and expert commentary

A Murji, K Biberoğlu, J Leng, MD Mueller… - … medical research and …, 2020 - Taylor & Francis
Objective: Endometriosis affects up to 10% of women of reproductive age, and the main goal
of treatment is to relieve symptoms. Progestins have been the mainstay of endometriosis …

[HTML][HTML] Long-term medical management of endometriosis with dienogest and with a gonadotropin-releasing hormone agonist and add-back hormone therapy

MA Bedaiwy, C Allaire, S Alfaraj - Fertility and sterility, 2017 - Elsevier
Endometriosis can recur after either surgical or medical therapy. Long-term medical therapy
is implemented to treat symptoms or prevent recurrence. Dienogest and gonadotropin …

[HTML][HTML] Norethindrone acetate or dienogest for the treatment of symptomatic endometriosis: a before and after study

P Vercellini, B Bracco, P Mosconi, A Roberto… - Fertility and sterility, 2016 - Elsevier
Objective To assess the proportion of patients satisfied with their treatment before and after a
systematic change from norethindrone acetate to dienogest as the first-line progestin for …

Long-term treatment of endometriosis with dienogest: retrospective analysis of efficacy and safety in clinical practice

T Römer - Archives of gynecology and obstetrics, 2018 - Springer
Purpose Endometriosis is a debilitating disease with high recurrence rates requiring long-
term management. Progestins such as dienogest are used empirically when first symptoms …

Current understanding on pharmacokinetics, clinical efficacy and safety of progestins for treating pain associated to endometriosis

F Barra, C Scala, S Ferrero - Expert opinion on drug metabolism & …, 2018 - Taylor & Francis
Introduction: Endometriosis is a chronic estrogen and progestogen responsive inflammatory
disease associated with pain symptoms and infertility. The medical therapy of endometriosis …

Real world data on symptomology and diagnostic approaches of 27,840 women living with endometriosis

K Becker, K Heinemann, B Imthurn, L Marions… - Scientific reports, 2021 - nature.com
Endometriosis is a chronic disease that requires a suitable, lifelong treatment. To our
knowledge, the Vi sanne P ost-approval O bservational S tudy (VIPOS) is to date the largest …

Flavonoids quercetin and kaempferol are NR4A1 antagonists and suppress endometriosis in female mice

L Zhang, K Mohankumar, G Martin, F Mariyam… - …, 2023 - academic.oup.com
Abstract Nuclear receptor 4A1 (NR4A1) plays an important role in endometriosis
progression; levels of NR4A1 in endometriotic lesions are higher than in normal …

Effect of Dienogest therapy on the size of the endometrioma

M Vignali, GM Belloni, G Pietropaolo… - Gynecological …, 2020 - Taylor & Francis
Studies have been published on the efficacy of Dienogest in the management of pain
symptoms in endometriosis. Nonetheless, few data are available on the reducing effect on …