Cellular therapeutic approaches to cytomegalovirus infection following allogeneic stem cell transplantation
Cytomegalovirus (CMV) infection is common following allogeneic hematopoietic stem cell
transplant (HSCT) and is a major cause of morbidity and increased mortality. Whilst …
transplant (HSCT) and is a major cause of morbidity and increased mortality. Whilst …
T-cell-based immunotherapies for haematological cancers, Part B: A SWOT analysis of adoptive cell therapies
KS Rallis, CRT Hillyar, M Sideris… - Anticancer Research, 2021 - ar.iiarjournals.org
Haematology has been at the forefront of cancer immunotherapy advancements. Allogeneic
haematopoietic stem cell transplant (allo-HSCT) is one of the earliest forms of cancer …
haematopoietic stem cell transplant (allo-HSCT) is one of the earliest forms of cancer …
[HTML][HTML] A novel xenogeneic graft-versus-host disease model for investigating the pathological role of human CD4+ or CD8+ T cells using immunodeficient NOG mice
R Ito, I Katano, K Kawai, M Yagoto, T Takahashi… - American Journal of …, 2017 - Elsevier
Graft-versus-host disease (GVHD) is a major complication of allogenic bone marrow
transplantation and involves the infiltration of donor CD4+ and/or CD8+ T cells into various …
transplantation and involves the infiltration of donor CD4+ and/or CD8+ T cells into various …
Robust identification of suitable T-cell subsets for personalized CMV-specific T-cell immunotherapy using CD45RA and CD62L microbeads
C Mangare, S Tischer-Zimmermann, SB Riese… - International Journal of …, 2019 - mdpi.com
Viral infections and reactivations remain a serious obstacle to successful hematopoietic
stem cell transplantation (HSCT). When antiviral drug treatment fails, adoptive virus-specific …
stem cell transplantation (HSCT). When antiviral drug treatment fails, adoptive virus-specific …
Specific removal of alloreactive T-cells to prevent GvHD in hemopoietic stem cell transplantation: rationale, strategies and perspectives
GL Pira, S Di Cecca, M Montanari, L Moretta, F Manca - Blood Reviews, 2016 - Elsevier
Hemopoietic stem cell transplantation (HSCT) is a standard procedure for treatment of
malignant and non-malignant hematological diseases. HSCT donors include HLA-identical …
malignant and non-malignant hematological diseases. HSCT donors include HLA-identical …
CCR7+ selected gene-modified T cells maintain a central memory phenotype and display enhanced persistence in peripheral blood in vivo
G Kueberuwa, H Gornall, EM Alcantar-Orozco… - … for Immunotherapy of …, 2017 - Springer
Background Adoptive T cell immunotherapy (ATCT) for cancer entails infusing patients with
T cells that recognise and destroy tumour cells. Efficient engraftment of T cells and …
T cells that recognise and destroy tumour cells. Efficient engraftment of T cells and …
Novel CD62L depleted donor lymphocyte infusion with T-cell receptor alpha-beta depleted haploidentical hematopoietic stem cell transplantation in children
Ex-vivo depletion of donor CD45RA+ naïve T-cells can reduce graft-versus-host-disease
(GVHD) in haploidentical hematopoietic stem cell transplantation (HSCT) while providing …
(GVHD) in haploidentical hematopoietic stem cell transplantation (HSCT) while providing …
Opportunities for Therapies for Graft-versus-host disease Following Hematopoietic Stem Cell Transplantation: Is Africa Prepared?
C Mangare - Journal of Medical and Biomedical Laboratory …, 2024 - jmblsr.com
Hematopoietic stem cell transplantation is a therapeutic approach used to cure many
malignant and non-malignant, acquired and congenital/genetic as well as benign disorders …
malignant and non-malignant, acquired and congenital/genetic as well as benign disorders …
A novel and efficient method to induce allospecific CD8+ memory T lymphocytes
L Yang, Q Huang, J Fu, Z Lin, Q Mao… - Journal of Clinical …, 2021 - Wiley Online Library
The aim of the current study was to establish a simple method for effectively inducing
memory T lymphocytes by the intraperitoneal injection of spleen lymphocytes into mice. In …
memory T lymphocytes by the intraperitoneal injection of spleen lymphocytes into mice. In …
[PDF][PDF] Identification of Suitable T-Cell Subsets for Personalized Antiviral T-Cell Immunotherapy
C Mangare - 2021 - d-nb.info
Post-transplant morbidity and mortality after allogeneic hematopoietic stem cell
transplantation (HSCT) and solid organ transplantation (SOT) are mainly caused by relapse …
transplantation (HSCT) and solid organ transplantation (SOT) are mainly caused by relapse …