Immuno-oncology is an emerging field that has revolutionized cancer treatment. Most
immunomodulatory strategies focus on enhancing T cell responses, but there has been a …

NKG2D is an activating receptor expressed by all NK cells and subsets of T cells. It serves
as a major recognition receptor for detection and elimination of transformed and infected …

In recent years, roles of the immune system in immune surveillance of cancer have been
explored using a variety of approaches. The roles of the adaptive immune system have been …

The importance of the immune system in conferring protection against pathogens like
viruses, bacteria, and parasitic worms is well established. In contrast, there is a long-lasting …

Natural killer (NK) cells are large granular lymphocytes involved in our defense against
certain virus-infected and malignant cells. In contrast to T cells, NK cells elicit rapid anti …

Natural killer group 2, member D (NKG2D) is an activating receptor present on the surface of
natural killer (NK) cells, some NKT cells, CD8+ cytotoxic T cells, γδ T cells, and under certain …

The activating receptor natural killer group 2, member D (NKG2D) is involved in both innate
and adaptive immunities, and functions as a “master switch” in determining the activation …

Abstract The Natural Killer Group 2D (NKG2D) receptor plays an important role in protecting
the host from infections and cancer. By recognizing ligands induced on infected or tumor …

Immunological control may contribute to achievement of deep molecular response in chronic
myeloid leukemia (CML) patients on tyrosine kinase inhibitor (TKI) therapy and may promote …

Herpesviruses are known for their persistent lifelong latent infection, which is made possible
by their vast repertoire of immune-evasion strategies. We have previously shown that a …