[HTML][HTML] Anisotropic scaffolds for peripheral nerve and spinal cord regeneration

W Xue, W Shi, Y Kong, M Kuss, B Duan - Bioactive materials, 2021 - Elsevier
The treatment of long-gap (> 10 mm) peripheral nerve injury (PNI) and spinal cord injury
(SCI) remains a continuous challenge due to limited native tissue regeneration capabilities …

Controlling the morphology and outgrowth of nerve and neuroglial cells: The effect of surface topography

C Simitzi, A Ranella, E Stratakis - Acta biomaterialia, 2017 - Elsevier
Unlike other tissue types, like epithelial tissue, which consist of cells with a much more
homogeneous structure and function, the nervous tissue spans in a complex multilayer …

3D microporous scaffolds manufactured via combination of fused filament fabrication and direct laser writing ablation

M Malinauskas, S Rekštytė, L Lukoševičius, S Butkus… - Micromachines, 2014 - mdpi.com
A 3D printing fused filament fabrication (FFF) approach has been implemented for the
creation of microstructures having an internal 3D microstructure geometry. These objects …

Engineered cell culture microenvironments for mechanobiology studies of brain neural cells

L Castillo Ransanz, PFJ Van Altena… - … in bioengineering and …, 2022 - frontiersin.org
The biomechanical properties of the brain microenvironment, which is composed of different
neural cell types, the extracellular matrix, and blood vessels, are critical for normal brain …

High aspect ratio and light-sensitive micropillars based on a semiconducting polymer optically regulate neuronal growth

F Milos, G Tullii, F Gobbo, F Lodola… - … Applied Materials & …, 2021 - ACS Publications
Many nano-and microstructured devices capable of promoting neuronal growth and network
formation have been previously investigated. In certain cases, topographical cues have …

Laser fabricated discontinuous anisotropic microconical substrates as a new model scaffold to control the directionality of neuronal network outgrowth

C Simitzi, P Efstathopoulos, A Kourgiantaki, A Ranella… - Biomaterials, 2015 - Elsevier
Patterning of neuronal outgrowth in vitro is important in tissue engineering as well as for the
development of neuronal interfaces with desirable characteristics. To date, this has been …

4D Biofabrication of fibrous artificial nerve graft for neuron regeneration

I Apsite, G Constante, M Dulle, L Vogt, A Caspari… - …, 2020 - iopscience.iop.org
In this paper, we describe the application of the 4D biofabrication approach for the
fabrication of artificial nerve graft. Bilayer scaffolds consisting of uniaxially aligned …

Advances in 3D printing scaffolds for peripheral nerve and spinal cord injury repair

J Song, B Lv, W Chen, P Ding… - International Journal of …, 2023 - iopscience.iop.org
Because of the complex nerve anatomy and limited regeneration ability of natural tissue, the
current treatment effect for long-distance peripheral nerve regeneration and spinal cord …

Cell patterning via laser micro/nano structured silicon surfaces

C Yiannakou, C Simitzi, A Manousaki, C Fotakis… - …, 2017 - iopscience.iop.org
The surface topography of biomaterials can have an important impact on cellular adhesion,
growth and proliferation. Apart from the overall roughness, the detailed morphological …

Femtosecond laser shockwave peening ablation in liquids for hierarchical micro/nanostructuring of brittle silicon and its biological application

D Zhang, LC Wu, M Ueki, Y Ito… - International Journal of …, 2020 - iopscience.iop.org
This paper presents a new technique, termed femtosecond laser shock peening ablation in
liquids (fs-LSPAL), which can realize simultaneous crack micro/nanomanufacturing and …