Tendons and ligaments are connective tissues that guide motion, share loads, and transmit
forces in a manner that is unique to each as well as the anatomical site and biomechanical …

Tendon consists of highly ordered type I collagen molecules that are grouped together to
form subunits of increasing diameter. At each hierarchical level, the type I collagen is …

The small leucine-rich proteoglycans (SLRPs), decorin and biglycan, are key regulators of
collagen fibril and matrix assembly. The goal of this work was to elucidate the roles of …

Tendons are dense connective tissues with a hierarchical polarized structure that respond to
and adapt to the transmission of muscle contraction forces to the skeleton, enabling motion …

Joint biomechanical functions rely on the integrity of cartilage extracellular matrix.
Understanding the molecular activities that govern cartilage matrix assembly is critical for …

The aging population is at an increased risk of tendon injury and tendinopathy. Elucidating
the molecular basis of tendon aging is crucial to understanding the age-related changes in …

Collagen XI is a fibril-forming collagen that regulates collagen fibrillogenesis. Collagen XI is
normally associated with collagen II-containing tissues such as cartilage, but it also is …

The structural dynamics of thin-walled parts vary as the material is removed during
machining. This paper presents a new, computationally efficient reduced order dynamic …

This review highlights recent research on structure–function relationships in tendon and
comments on the parallels between development and healing. The processes of tendon …

Extracellular matrix (ECM) determines the physiological function of all tissues, including
musculoskeletal tissues. In tendon, ECM provides overall tissue architecture, which is …