An update on current pharmacotherapeutic options for the treatment of ulcerative colitis

F Ferretti, R Cannatelli, MC Monico, G Maconi… - Journal of Clinical …, 2022 - mdpi.com
The main goals of Ulcerative Colitis (UC) treatment are to both induce and maintain the
clinical and endoscopic remission of disease, reduce the incidence of complications such as …

Management of non-response and loss of response to anti-tumor necrosis factor therapy in inflammatory bowel disease

J Marsal, M Barreiro-de Acosta, I Blumenstein… - Frontiers in …, 2022 - frontiersin.org
Anti-tumor necrosis factor (anti-TNF) therapy has been successfully used as first-line
biologic treatment for moderate-to-severe inflammatory bowel disease (IBD), in both “step …

ECCO guidelines on therapeutics in ulcerative colitis: medical treatment

T Raine, S Bonovas, J Burisch… - Journal of Crohn's …, 2022 - academic.oup.com
Ulcerative colitis [UC] is a chronic inflammatory bowel disease [IBD] characterised by colonic
inflammation extending to a variable extent from the rectum. Care of the patient with UC …

Versatile carbon dots with superoxide dismutase-like nanozyme activity and red fluorescence for inflammatory bowel disease therapeutics

Y Ma, J Zhao, L Cheng, C Li, X Yan, Z Deng, Y Zhang… - Carbon, 2023 - Elsevier
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease
(CD), is a chronic and recurrent disease that seriously affects the life quality of patients …

Pediatric inflammatory bowel disease

M Bouhuys, WS Lexmond, PF van Rheenen - Pediatrics, 2023 - publications.aap.org
Inflammatory bowel diseases (IBDs) are chronic, immune-mediated disorders that include
Crohn's disease and ulcerative colitis. A pediatric onset of disease occurs in about 10% of …

Necrosulfonamide ameliorates intestinal inflammation via inhibiting GSDMD-medicated pyroptosis and MLKL-mediated necroptosis

W Yang, K Tao, Y Wang, Y Huang, C Duan… - Biochemical …, 2022 - Elsevier
Inflammatory bowel disease (IBD) is a chronic relapsing disorder of the gastrointestinal tract,
while the present therapeutic efficacy is insufficient. In recent years, numerous studies have …

Safety of Janus kinase inhibitors in inflammatory bowel diseases

P Núñez, R Quera, AJ Yarur - Drugs, 2023 - Springer
In recent years, better knowledge of the pathophysiology of inflammatory bowel diseases
(IBD) has led to a relevant expansion of the therapeutic arsenal for these conditions. Janus …

Practical management of mild-to-moderate ulcerative colitis: an international expert consensus

F D'Amico, F Magro, A Dignass… - Expert Review of …, 2024 - Taylor & Francis
Introduction Although there are well-defined guidelines for the management of mild-to-
moderate ulcerative colitis (UC), there are still unmet needs. For this reason, we conducted …

Systematic review with network meta‐analysis: Risk of Herpes zoster with biological therapies and small molecules in inflammatory bowel disease

S Din, CP Selinger, CJ Black… - Alimentary Pharmacology …, 2023 - Wiley Online Library
Background Biologics and small molecules for inflammatory bowel disease (IBD) may
increase infection risk. Herpes zoster causes acute and long‐term symptoms, but …

[HTML][HTML] Tofacitinib and newer JAK inhibitors in inflammatory bowel disease—where we are and where we are going

E Liu, N Aslam, G Nigam, JK Limdi - Drugs in Context, 2022 - ncbi.nlm.nih.gov
Inflammatory bowel diseases, comprising ulcerative colitis (UC) and Crohn's disease, are
chronic, immune-mediated and progressive inflammatory disorders affecting the …