Perceptual abnormalities such as hyperacusis and tinnitus often occur after acoustic
overexposure. Although such exposure can also result in permanent threshold elevation …

Inhibition plays a crucial role in many functional domains, such as cognition, emotion, and
actions. Studies on cognitive aging demonstrate changes in inhibitory mechanisms are age …

Acoustic startle response (ASR) modification procedures, especially prepulse inhibition
(PPI), are increasingly used as behavioral measures of auditory processing and …

Prepulse inhibition (PPI) is the suppression of a startle reflex response to a startle stimulus
that occurs when a weak prepulse stimulus precedes the startle stimulus. PPI is measured to …

Background: Prepulse-induced startle modulation occurs when a weak sensory stimulus
('prepulse') is presented before a startling sensory stimulus ('pulse'), producing an inhibited …

In order to better understand animal models of Alzheimer's disease, novel phenotyping
strategies have been established for transgenic mouse models. In line with this, the current …

Tinnitus is the perception of a sound that has no external source. Sound stimuli can
suppress spontaneous firing in auditory neurons long after stimulus offset. It is unknown how …

Startle reflex is modulated when a weaker sensory stimulus (“prepulse”) precedes a startling
stimulus (“pulse”). Prepulse Inhibition (PPI) is the attenuation of the startle reflex (prepulse …

Prepulse inhibition (PPI) of the startle response is sensitive to sex, with healthy young
women showing less PPI compared with age-matched men, and varies according to the …

Testosterone influences the hypothalamic–pituitary–adrenal axis, anxiety-related behavior,
and sensorimotor gating in rodents, but little is known about the role of the androgen …