Abstract I. Introduction 00 II. Reactive Oxygen and Nitrogen Species 00 III. Biological
Markers of Oxidative/Nitrosative Stress 00 IV. Oxidative/Nitrosative Stress and Protein …

Increasing evidence suggests that asthma is a heterogeneous disorder regulated by distinct
molecular mechanisms. In a cross-sectional study of asthmatics of varying severity (n= 51) …

To investigate whether the inflammatory process in peripheral airways is different in smokers
who develop symptoms of chronic bronchitis and chronic airflow limitation and in …

To identify airway pathologic abnormalities selectively associated with severe asthma, we
examined 10 control subjects, 10 patients with intermittent asthma, 15 patients with mild-to …

In order to investigate the relationship between airways inflammation and disease severity,
and improve the understanding of persistent asthma, 74 asthmatics, with disease severity …

Allergen-reactive T helper type-2 (Th2) cells and proinflammatory cytokines have been
suggested to play an important role in the induction and maintenance of the inflammatory …

The pulmonary route is an interesting route for drug administration, both for effective local
therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the …

Cellular events that occur in status asthmaticus (SA) remain poorly investigated. Autopsy
studies frequently emphasized about the presence of eosinophils in bronchial airway wall …

Background Little is known about the relationship between airway inflammatory phenotypes
and some important asthma features such as small airway dysfunction (SAD). Objective To …

It has been suggested that patients with refractory eosinophilic airway inflammation
represent a separate “eosinophilic” asthma phenotype associated with increased morbidity …