Chronic critical illness and post-intensive care syndrome: from pathophysiology to clinical challenges

G Voiriot, M Oualha, A Pierre… - Annals of intensive …, 2022 - Springer
Background Post‐intensive care syndrome (PICS) encompasses physical, cognition, and
mental impairments persisting after intensive care unit (ICU) discharge. Ultimately it …

Comfort and patient-centred care without excessive sedation: the eCASH concept

JL Vincent, Y Shehabi, TS Walsh… - Intensive care …, 2016 - Springer
We propose an integrated and adaptable approach to improve patient care and clinical
outcomes through analgesia and light sedation, initiated early during an episode of critical …

Chronic pain after COVID-19: implications for rehabilitation

HI Kemp, E Corner, LA Colvin - British journal of anaesthesia, 2020 - bjanaesthesia.org
Managing the immediate demands of the current coronavirus disease 2019 (COVID-19)
global pandemic has tested many healthcare systems across the world, to their limits. As we …

The ABCDEF bundle: science and philosophy of how ICU liberation serves patients and families

EW Ely - Critical care medicine, 2017 - journals.lww.com
Over the past 20 years, critical care has matured in a myriad of ways resulting in dramatically
higher survival rates for our sickest patients. For millions of new survivors comes de novo …

[PDF][PDF] ICU delirium—a diagnostic and therapeutic challenge in the intensive care unit

K Kotfis, A Marra, EW Ely - Anaesthesiology intensive therapy, 2018 - termedia.pl
ICU delirium is a common medical problem occurring in patients admitted to the intensive
care units (ICUs). Studies have shown that ICU delirium is associated with increased …

Association of delirium response and safety of pharmacological interventions for the management and prevention of delirium: a network meta-analysis

YC Wu, PT Tseng, YK Tu, CY Hsu, CS Liang… - JAMA …, 2019 - jamanetwork.com
Importance Although several pharmacological interventions for delirium have been
investigated, their overall benefit and safety remain unclear. Objective To evaluate evidence …

Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)

JL Vincent, JY Lefrant, K Kotfis, R Nanchal… - Intensive care …, 2018 - Springer
Purpose To evaluate differences in the characteristics and outcomes of intensive care unit
(ICU) patients over time. Methods We reviewed all epidemiological data, including …

Delirium and long term cognition in critically ill patients

ME Wilcox, TD Girard, CL Hough - bmj, 2021 - bmj.com
Delirium, a form of acute brain dysfunction, is very common in the critically ill adult patient
population. Although its pathophysiology is poorly understood, multiple factors associated …

High sedation needs of critically ill COVID-19 ARDS patients—A monocentric observational study

AN Flinspach, H Booke, K Zacharowski, Ü Balaban… - PloS one, 2021 - journals.plos.org
Background Therapy of severely affected coronavirus patient, requiring intubation and
sedation is still challenging. Recently, difficulties in sedating these patients have been …

Delirium in the intensive care unit

S Arumugam, A El-Menyar, A Al-Hassani… - … , trauma, and shock, 2017 - journals.lww.com
Delirium is characterized by impaired cognition with nonspecific manifestations. In critically
ill patients, it may develop secondary to multiple precipitating or predisposing causes …