Offers essential guidance for discovering and optimizing novel drug therapies Using
detailed examples, Evaluation of Enzyme Inhibitors in Drug Discovery equips researchers …

This review highlights recent advances in the application of electrospray ionisation and
matrix-assisted laser desorption/ionisation mass spectrometry (MS) to study enzymatic …

Modern mass spectrometry-the instrumentation and applications in diverse fields Mass
spectrometry has played a pivotal role in a variety of scientific disciplines. Today it is an …

Mass spectrometry (MS) has been applied to drug discovery for many years. With the advent
of new ionization techniques, MS has emerged as an important analytical tool in …

Lipases and esterases constitute a large category of enzymes. They are ubiquitous in
nature, found in bacteria, fungi, and animals. The family members address a wide variety of …

The development of electrospray ionization (ESI) for biomolecular analysis marks one of the
historically significant events in mass spectrometry (MS).[1] As a consequence largely of …

Since the advent of matrix-assisted laser desorption/ionization and electrospray ionization,
mass spectrometry has played an increasingly important role in protein functional …

Matrix-assisted laser desorption/ionization time-of-flight (MALDI-ToF) mass spectrometry
(MS) imaging has been used for rapid phenotyping of enzymatic activities, but is mainly …

The number of reported cases of chronic arsenic poisoning is on the rise throughout the
world, making the study of the long-term effects of arsenic critical. As3+ binds readily to …

The inhibition effect of the selected heavy metals (Ag+, Cd2+, Cu2+, and Hg2+) on glucose
oxidase (GOx) enzyme from Aspergillus niger (EC 1.1. 3.4.) was studied using a new …