Alzheimer's disease (AD) is considered a polygenic disorder. This view is clouded, however,
by lingering uncertainty over how to treat the quasi" monogenic" role of apolipoprotein E …

Age and apolipoprotein E (ApoE) are the mightiest risk factors for dementia and
cardiovascular diseases, but the underlying mechanisms remain unclear. In human, ApoE …

Importance Individual conditions have been identified as risk factors for dementia; however,
it is important to consider the role of multimorbidity, as conditions often co-occur. Objective …

Ischemic stroke is a sudden loss of brain function due to the reduction of blood flow. Brain
tissues cease to function with subsequent activation of the ischemic cascade. Metabolomics …

Vascular contributions to cognitive impairment and dementia (VCID) are a common cause of
cognitive decline, yet limited therapies exist. This cerebrovascular disease results in …

Background and aims Genetic studies have been reported on the association between
APOA5, APOB, APOC3 and ABCA1 gene polymorphisms and ischemic stroke, but results …

Objectives Oxidative stress and inflammation have a critical role in the pathogenesis of
ischaemic stroke. Alpha-pinene is a monoterpenoid molecule with anti-inflammatory and …

Frontotemporal dementia (FTD), dementia with Lewy bodies (DLB) and vascular dementia
(VaD) are the most common forms of dementia after Alzheimer's disease (AD). The …

Background The comorbidity of major depressive disorder (MDD) and stroke are common in
clinic. There is a growing body of evidence suggesting a bi-directional relationship between …

AIM To update and investigate the clinical outcomes and complications between
femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification …