An increased intestinal permeability has been described in various gastrointestinal and non-
gastrointestinal disorders. Nevertheless, the concept and definition of intestinal permeability …

Intestinal permeation enhancers (PEs) are one of the most widely tested strategies to
improve oral delivery of therapeutic peptides. This article assesses the intestinal permeation …

Organs-on-chips are a new class of microengineered laboratory models that combine
several of the advantages of current in vivo and in vitro models. In this review, we summarize …

An essential role of the intestinal epithelium is to separate luminal contents from the
interstitium, a function primarily determined by the integrity of the epithelium and the tight …

In multicellular organisms epithelial and endothelial cells form selective permeable
interfaces between tissue compartments of different chemical compositions. Tight junctions …

The blood–brain barrier (BBB) represents the tightest endothelial barrier within the
cardiovascular system characterized by very low ionic permeability. Our aim was to describe …

Epithelial transport relies on the proper function and regulation of the tight junction (TJ),
other‐wise uncontrolled paracellular leakage of solutes and water would occur. They also …

Growth impairment is a major public health issue for children in Tanzania. The question
remains as to whether dietary mycotoxins play a role in compromising children's growth. We …

The application of permeation enhancers (PEs) to improve transport of poorly absorbed
active pharmaceutical ingredients across the intestinal epithelium is a widely tested …

The paracellular barrier of epithelia and endothelia is established by several tight junction
proteins including claudin-3. Although claudin-3 is present in many epithelia including skin …