Covering: 2016. Previous review: Nat. Prod. Rep., 2017, 34, 235–294 This review covers the
literature published in 2016 for marine natural products (MNPs), with 757 citations (643 for …

The oceans are a rich source of a myriad of structurally different and unique natural products
that are mainly found in invertebrates with potential applications in different disciplines …

Marine alkaloid rigidins are cytotoxic compounds known to kill cancer cells at nanomolar
concentrations by targeting the microtubule network. Here, a rigidin analogue containing a …

Photoactivated chemotherapy (PACT) is a promising cancer treatment modality that kills
cancer cells via photochemical uncaging of a cytotoxic drug. Most ruthenium‐based …

This review covers recent literature from 2012-2019 concerning 170 marine natural products
and their semisynthetic analogues with strong anticancer biological activities. Reports that …

Marine natural products as secondary metabolites are a potential major source of new drugs
for treating disease. In some cases, cytotoxic marine metabolites target the microtubules of …

Marine alkaloids comprise a class of compounds with several nitrogenated structures that
can be explored as potential natural bioactive compounds. The scientific interest in these …

To improve their aqueous solubility characteristics, water-solubilizing groups were added to
some antiproliferative, rigidin-inspired 7-deazahypoxanthine frameworks after molecular …

Non-small-cell lung cancer (NSCLC) dominates over 85% of all lung cancer cases.
Epidermal growth factor receptor (EGFR) activating mutation is a common situation in …

The stimulator of the interferon gene (STING) signaling pathway acts as a primary defense
system against DNA pathogens. Because of the crucial role of STING in type I interferon …