Realizing the clinical utility of saliva for monitoring oral diseases

JL Ebersole, H Hasturk, M Huber… - Periodontology …, 2024 - Wiley Online Library
In the era of personalized/precision health care, additional effort is being expended to
understand the biology and molecular mechanisms of disease processes. How these …

aMMP-8 oral fluid PoC test in relation to oral and systemic diseases

T Sorsa, SO Nwhator, D Sakellari, A Grigoriadis… - Frontiers in oral …, 2022 - frontiersin.org
The manuscript uses the previously published literature and highlights the benefits of active-
matrix metalloproteinase (aMMP)-8 chairside/point-of-care (PoC) diagnostic tools as …

Phase IIa clinical trial of complement C3 inhibitor AMY-101 in adults with periodontal inflammation

H Hasturk, G Hajishengallis, JD Lambris… - The Journal of …, 2021 - Am Soc Clin Investig
Background Gingivitis and periodontitis are prevalent inflammatory diseases of the
periodontal tissues. Current treatments are often ineffective or do not prevent disease …

Peri-implant diseases diagnosis, prognosis and dental implant monitoring: a narrative review of novel strategies and clinical impact

R Bornes, J Montero, A Correia, T Marques, N Rosa - BMC Oral Health, 2023 - Springer
Background The diagnosis of peri-implantar and periodontal relies mainly on a set of clinical
measures and the evaluation of radiographic images. However, these clinical settings alone …

Precision periodontal care: from omics discoveries to chairside diagnostics

N Bostanci, GN Belibasakis - Clinical Oral Investigations, 2023 - Springer
The interface of molecular science and technology is guiding the transformation of
personalized to precision healthcare. The application of proteomics, genomics …

Active matrix metalloproteinase‐8: A potential biomarker of oral systemic link

K Umeizudike, I Räisänen, S Gupta… - Clinical and …, 2022 - Wiley Online Library
Objectives This mini review aims to address some possible gaps in periodontal diagnosis in
clinical studies particularly involving the oral‐systemic connection with a view to minimize …

Active MMP‐8 point‐of‐care (PoC)/chairside enzyme‐test as an adjunctive tool for early and real‐time diagnosis of peri‐implantitis

H Lähteenmäki, T Tervahartiala… - Clinical and …, 2022 - Wiley Online Library
Objective The aim of this study was to investigate the utility of the active matrix
metalloproteinase (aMMP‐8)‐point‐of‐care (PoC) test as a quantitative real‐time chair‐side …

Impact of COVID-19 on periodontitis and peri-implantitis: a narrative review

L Mancini, LM Americo, T Pizzolante, R Donati… - Frontiers in Oral …, 2022 - frontiersin.org
COVID-19 is reported as one of the most widespread diseases in the world. An extraordinary
number of articles and manuscripts have focused on the inflammatory cascade and …

The main bacterial communities identified in the sites affected by periimplantitis: A systematic review

SAL Iușan, OP Lucaciu, NB Petrescu, IC Mirică… - Microorganisms, 2022 - mdpi.com
(1) Background: Periimplantitis is an infectious condition that affects the periimplant tissue
and is of bacterial etiology. However, to date, the exact bacterial flora involved in its …

Antimicrobial and Anti-Inflammatory Oral Effects of Fermented Lingonberry Juice—A One-Year Prospective Human Intervention Study

P Pärnänen, S Lomu, IT Räisänen… - European Journal of …, 2023 - thieme-connect.com
Objectives A 1-year prospective human intervention study was performed to examine the
anticaries, anti-inflammatory, antiproteolytic, and antimicrobial effects of fermented …