Single-cell technologies, particularly single-cell RNA sequencing (scRNA-seq) methods,
together with associated computational tools and the growing availability of public data …

Methods for profiling RNA and protein expression in a spatially resolved manner are rapidly
evolving, making it possible to comprehensively characterize cells and tissues in health and …

Single-cell RNA-sequencing has become a powerful tool to study biologically significant
characteristics at explicitly high resolution. However, its application on emerging data is …

Formation of oriented myofibrils is a key event in musculoskeletal development. However,
the mechanisms that drive myocyte orientation and fusion to control muscle directionality in …

Single-cell technologies are revolutionizing the entire field of biology. The large volumes of
data generated by single-cell technologies are high dimensional, sparse, and …

Single-cell RNA sequencing (scRNA-Seq) is a recent technology that allows for the
measurement of the expression of all genes in each individual cell contained in a sample …

Krüppel-like factor 9 (Klf9) is a ubiquitously expressed transcription factor that is a
feedforward regulator of multiple stress-responsive and endocrine signaling pathways. We …

Accurately identifies the cellular composition of complex tissues, which is critical for
understanding disease pathogenesis, early diagnosis, and prevention. However, current …

Introduction: Non-small cell lung cancer (NSCLC) exhibits heterogeneity with diverse
immune cell infiltration patterns that can influence tumor cell behavior and immunotherapy …

The study of immunology, traditionally reliant on proteomics to evaluate individual immune
cells, has been revolutionized by single-cell RNA sequencing. Computational …