Glymphatic imaging using MRI

T Taoka, S Naganawa - Journal of Magnetic Resonance …, 2020 - Wiley Online Library
In recent years, the existence of a mass transport system in the brain via cerebrospinal fluid
(CSF) or interstitial fluid (ISF) has been suggested by many studies. The glymphatic system …

Establishing a framework for neuropathological correlates and glymphatic system functioning in Parkinson's disease

S Sundaram, RL Hughes, E Peterson… - Neuroscience & …, 2019 - Elsevier
Recent evidence has advanced our understanding of the function of sleep to include
removal of neurotoxic protein aggregates via the glymphatic system. However, most …

Association of sleep, neuropsychological performance, and gray matter volume with glymphatic function in community-dwelling older adults

TY Siow, CH Toh, JL Hsu, GH Liu, SH Lee, NH Chen… - Neurology, 2022 - AAN Enterprises
Background and Objectives The glymphatic system, which is robustly enabled during some
stages of sleep, is a fluid-transport pathway that clears cerebral waste products. Most …

[HTML][HTML] Novel developments in non-contrast enhanced MRI of the perivascular clearance system: What are the possibilities for Alzheimer's disease research?

MM van der Thiel, WH Backes, IHGB Ramakers… - Neuroscience & …, 2023 - Elsevier
The cerebral waste clearance system (ie, glymphatic or intramural periarterial drainage)
works through a network of perivascular spaces (PVS). Dysfunction of this system likely …

[HTML][HTML] Assessing pulsatile waveforms of paravascular cerebrospinal fluid dynamics within the glymphatic pathways using dynamic diffusion-weighted imaging (dDWI …

Q Wen, Y Tong, X Zhou, M Dzemidzic, CY Ho, YC Wu - Neuroimage, 2022 - Elsevier
Cerebrospinal fluid (CSF) in the paravascular spaces of the surface arteries (sPVS) is a vital
pathway in brain waste clearance. Arterial pulsations may be the driving force of the …

Changing the currently held concept of cerebrospinal fluid dynamics based on shared findings of cerebrospinal fluid motion in the cranial cavity using various types of …

M Matsumae, K Kuroda, S Yatsushiro… - Neurologia medico …, 2019 - jstage.jst.go.jp
The “cerebrospinal fluid (CSF) circulation theory” of CSF flowing unidirectionally and
circulating through the ventricles and subarachnoid space in a downward or upward fashion …

Assessment of factors influencing glymphatic activity and implications for clinical medicine

A Gędek, D Koziorowski, S Szlufik - Frontiers in Neurology, 2023 - frontiersin.org
The glymphatic system is a highly specialized fluid transport system in the central nervous
system. It enables the exchange of the intercellular fluid of the brain, regulation of the …

Diffusion magnetic resonance imaging of cerebrospinal fluid dynamics: Current techniques and future advancements

AM Wright, YC Wu, L Feng, Q Wen - NMR in Biomedicine, 2024 - Wiley Online Library
Cerebrospinal fluid (CSF) plays a critical role in metabolic waste clearance from the brain,
requiring its circulation throughout various brain pathways, including the ventricular system …

Clinical magnetic resonance imaging evaluation of glymphatic function

ED Boyd, J Kaur, G Ding, M Chopp… - NMR in …, 2024 - Wiley Online Library
The glymphatic system is a system of specialized perivascular spaces in the brain that
facilitates removal of toxic waste solutes from the brain. Evaluation of glymphatic system …

Limits to flow detection in phase contrast MRI

NH Williamson, ME Komlosh, D Benjamini… - Journal of magnetic …, 2020 - Elsevier
Pulsed gradient spin echo (PGSE) complex signal behavior becomes dominated by
attenuation rather than oscillation when displacements due to flow are similar or less than …