The S100 family of proteins contains 25 known members that share a high degree of
sequence and structural similarity. However, only a limited number of family members have …

The activation of host's innate and adaptive immune systems can lead to acute and chronic
graft rejection, which seriously impacts graft survival. Thus, it is particularly significant to …

Interstitial lung disease and associated fibrosis occur in a proportion of individuals who have
recovered from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

Neutrophils are versatile innate effector cells essential for immune defense but also
responsible for pathologic inflammation. This dual role complicates therapeutic targeting …

In this review we summarize recent major advances in our understanding on the molecular
mechanisms, mediators, and biomarkers of acute lung injury (ALI) and alveolar-capillary …

Unraveling the molecular mechanisms for COVID-19-associated encephalopathy and its
immunopathology is crucial for developing effective treatments. Here, we utilized single-cell …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) infection, is currently the
deadliest infectious disease in human that can evolve to severe forms. A comprehensive …

Airway mucus hyperproduction is a common feature of chronic airway diseases such as
severe asthma, chronic obstructive pulmonary disease and cystic fibrosis, which are closely …

Neutrophils are key pathogen exterminators of the innate immune system endowed with
oxidative and non-oxidative defense mechanisms. More recently, a more complex role for …

The measles, mumps, and rubella (MMR) vaccine protects against all-cause mortality in
children, but the immunological mechanisms mediating these effects are poorly known. We …