Bladder cancer: current challenges and future directions

J Dobruch, M Oszczudłowski - Medicina, 2021 - mdpi.com
Bladder cancer (BCa) is the most common malignancy of the urinary tract and one of the
most prevalent cancers worldwide. While the clinical approach to BCa has remained largely …

The prognostic and clinicopathological significance of systemic immune-inflammation index in bladder cancer

J Li, D Cao, Y Huang, Q Xiong, D Tan, L Liu… - Frontiers in …, 2022 - frontiersin.org
Background Systemic immune-inflammation index (SII) has recently emerged as a
biomarker for the prognosis of a variety of malignant tumors. However, the role of SII in …

MUC1 expression affects the immunoflogosis in renal cell carcinoma microenvironment through complement system activation and immune infiltrate modulation

G Lucarelli, GS Netti, M Rutigliano, F Lasorsa… - International Journal of …, 2023 - mdpi.com
Mucin1 (MUC1), a glycoprotein associated with an aggressive cancer phenotype and
chemoresistance, is aberrantly overexpressed in a subset of clear cell renal cell carcinoma …

Metabolomic approaches for detection and identification of biomarkers and altered pathways in bladder cancer

NA di Meo, D Loizzo, SD Pandolfo, R Autorino… - International Journal of …, 2022 - mdpi.com
Metabolomic analysis has proven to be a useful tool in biomarker discovery and the
molecular classification of cancers. In order to find new biomarkers, and to better understand …

BCG-unresponsive non-muscle-invasive bladder cancer: current treatment landscape and novel emerging molecular targets

F Claps, N Pavan, L Ongaro, D Tierno, G Grassi… - International journal of …, 2023 - mdpi.com
Urothelial carcinoma (UC), the sixth most common cancer in Western countries, includes
upper tract urothelial carcinoma (UTUC) and bladder carcinoma (BC) as the most common …

Systemic immune-inflammation index is a prognostic factor for breast cancer patients after curative resection

W Li, G Ma, Y Deng, W Chen, Z Liu, F Chen… - Frontiers in …, 2021 - frontiersin.org
Background The preoperative systemic immune-inflammation index (SII) is correlated with
prognosis in several malignancies. The aim of this study was to investigate the prognosis …

[HTML][HTML] Oncologic outcomes following radical nephroureterectomy for upper tract urothelial carcinoma: a literature review

G Grob, D Rogers, SD Pandolfo… - Translational …, 2023 - ncbi.nlm.nih.gov
Methods A non-systematic review of the literature was conducted by performing an
electronic literature search using PubMed with “radical nephroureterectomy” and “oncologic …

Prognostic role of neutrophil-to-lymphocyte ratio (NLR) in urological tumors: an umbrella review of evidence from systematic reviews and meta-analyses

G Mjaess, R Chebel, A Karam, I Moussa, D Pretot… - Acta …, 2021 - Taylor & Francis
Background Neutrophil-to-lymphocyte ratio (NLR) has been studied as a biomarker for
cancer prognosis, predicting survival in many tumors. The aim of this umbrella review was to …

Immune profiles and DNA methylation alterations related with non-muscle-invasive bladder cancer outcomes

JQ Chen, LA Salas, JK Wiencke, DC Koestler… - Clinical …, 2022 - Springer
Background Non-muscle-invasive bladder cancer (NMIBC) patients receive frequent
monitoring because≥ 70% will have recurrent disease. However, screening is invasive …

Treatment outcomes of high-risk non-muscle invasive bladder cancer (HR-NMIBC) in real-world evidence (RWE) studies: systematic literature review (SLR)

MG Musat, CS Kwon, E Masters, S Sikirica… - ClinicoEconomics …, 2022 - Taylor & Francis
Background To date, there has been limited synthesis of RWE studies in high-risk non-
muscle invasive bladder cancer (HR-NMIBC). The objective of this research was to conduct …