Cisplatin is a widely used chemotherapy agent in the treatment of various forms of
carcinomas and sarcomas. Its effectiveness in delaying negative outcome in cancer patients …

Cisplatin, cisplatinum, or cis-diamminedichloroplatinum (II), is a well-known
chemotherapeutic drug. It has been used for treatment of numerous human cancers …

Cervical cancer (CC) caused by human papillomavirus (HPV) is one of the largest causes of
malignancies in women worldwide. Cisplatin is one of the widely used drugs for the …

Emerging evidence suggests that cancer preventative agents might be combined with
chemotherapy or radiotherapy for the more effective treatment of cancer. Recent studies …

Abstract The steroid hormone 1, 25-dihydroxyvitamin D 3,[1, 25 (OH) 2 D 3, calcitriol], the
active metabolite of vitamin D, exerts pleiotropic antitumor effects against several …

Vitamin D has been recognized for more than a century as essential for the normal
development and mineralization of a healthy skeleton. More extensive roles for vitamin D …

Background Active vitamin D analogs that are less toxic than calcitriol can be useful in the
combined treatment of patients suffering from colon cancer. In the present study we …

Abstract Analogs of 1, 25-dihydroxyvitamin D 3 with a reversed configuration at C-1 or C-24
and E or Z geometry of the double bond at C-22 in the side chain or at C-5 in the triene …

5,141,719 A 8, 1992 Fernwood et al. 5,157,135 A 10/1992 Tsuji et al. 5,158,944 A 10, 1992
Makino 5, 182,274 A 1/1993 Makino 5,205,989 A 4/1993 Aysta 5,219,528 A 6, 1993 Clark …

Aim: The aim of this study was the evaluation of the antitumor effect of two synthetic analogs
of vitamin D, PRI-2191 and PRI-2205 in combined treatment with irinotecan or oxaliplatin on …