The extracellular matrix (ECM) is a complex network of biomolecules that mechanically and
biochemically directs cell behavior and is crucial for maintaining tissue function and health …

Tendons are collagen-rich musculoskeletal tissues that possess the mechanical strength
needed to transfer forces between muscles and bones. The mechanical development and …

Tendons have a uniaxially aligned structure with a hierarchical organization of collagen
fibrils crucial for tendon function. Collagen XII is expressed in tendons and has been …

Nonsteroidal anti-inflammatory drugs (NSAIDs) and periodic corticosteroid injections are
frequently used to treat tendinopathy. However, prior research clinical studies revealed that …

Tendon maturation lays the foundation for postnatal tendon development, its proper
mechanical function, and regeneration, but the critical cell populations and the entangled …

Dielectrophoresis (DEP), a nonlinear electrokinetic technique caused by Maxwell–Wagner
interfacial polarization of neutral particles in an electrolyte solution, is a powerful cell …

Mechanical loading may be required for proper tendon formation. However, it is not well
understood how tendon formation is impacted by the development of weight-bearing …

Tendon injury repair has been a clinical challenge, and little is known about tendon healing
scar generation, repair, and regeneration mechanisms. To explore the cellular composition …

Background Tissue engineered and regenerative approaches for treating tendon injuries
are challenged by the limited information on the cellular signaling pathways driving …

Tissue banking programs fail to meet the demand for human organs and tissues for
transplantation into patients with congenital defects, injuries, chronic diseases, and end …