Pyrazines are important class of pharmacophores because of their versatility in
pharmacological activity. Pyrazines are among the most widely known heterocyclic …

Publisher Summary This chapter reviews the syntheses and reactions of 6-membered
heterocyclic ring systems, such as diazines and benzo derivatives. The diazines pyridazine …

Compounds possessing benzimidazole system exhibit significant antituberculous activity. In
order to examine how structure modifications affect tuberculostatic activity, a series of …

A series of novel 3-cyclohexylpropanoic acid derivatives and 3-cyclohexylpropanoic acid-
derived nitrogen heterocyclic compounds (1–8) have been synthesized and evaluated for …

Abstract A series of novel 2-(2-phenalkyl)-1H-benzo [d] imidazole derivatives and analogues
(2a–3l) have been synthesized and evaluated for tuberculostatic activity. Benzimidazoles …

Reaction of 2-cyanopyrazine with thiosemicarbazide or N-methylthiosemicarbazide afforded
the (Z)-2-(amino (pyrazin-2-yl) methylene) hydrazinecarbothioamide (HPzAm4DH) and (Z)-2 …

Four novel methyl 4-phenylpicolinoimidate derivatives of hydrazone have been synthesized
and evaluated for their antimicrobial activity, including tuberculostatic activity. The …

A new series of 5-acetylbarbituric based thiosemicarbazones (TSC) named 5-
acetylbarbituric hydrazine-1-carbothioamide (1), N-methyl-(5-acetylbarbituric) hydrazine-1 …

Four compounds showing moderate antituberculostatic activity have been studied to test the
hypothesis that the planarity of the 2-[amino (pyrazin-2-yl) methylidene] dithiocarbazate …

Dimethyl (3, 4-dichlorobenzoyl) carbonohydrazonodithioate, C10H10Cl2N2OS2,(D1),
dibenzyl (3, 4-dichlorobenzoyl) carbonohydrazonodithioate, C22H18Cl2N2OS2,(D2) …