Age-associated epigenetic changes in mammalian sperm: implications for offspring health and development

V Ashapkin, A Suvorov, JR Pilsner… - Human reproduction …, 2023 - academic.oup.com
BACKGROUND Modern reproductive behavior in most developed countries is characterized
by delayed parenthood. Older gametes are generally less fertile, accumulating and …

Potential implications of sperm DNA methylation functional properties in aquaculture management

S Zhang, Y Cheng, P Věchtová… - Reviews in …, 2023 - Wiley Online Library
The biology of fish sperm, an important topic in the research of reproduction and fisheries
from basic science to evolutionary and applied aspects, has implications for aquaculture …

Contributions of epigenetic inheritance to the predisposition of major psychiatric disorders: Theoretical framework, evidence, and implications

RB Varela, JH Cararo, SJ Tye, AF Carvalho… - Neuroscience & …, 2022 - Elsevier
Susceptibility to psychiatric disorders seems to be influenced by environmental disturbances
throughout all stages of life. Epigenetics is described as a key “bridge” between gene and …

Association between paternal age and birth weight in preterm and full-term birth: a retrospective study

Y Mao, C Zhang, Y Wang, Y Meng, L Chen… - Frontiers in …, 2021 - frontiersin.org
Purpose While it is well documented that maternal adverse exposures contribute to a series
defects on offspring health according to the Developmental Origins of Health and Disease …

Decoding microRNAs in autism spectrum disorder

J Li, X Xu, J Liu, S Zhang, X Tan, Z Li, J Zhang… - … Therapy-Nucleic Acids, 2022 - cell.com
Autism spectrum disorder (ASD)—a congenital mental disorder accompanied by social
dysfunction and stereotyped behaviors—has attracted a great deal of attention worldwide. A …

Changes in Phenotypes and DNA Methylation of In Vitro Aging Sperm in Common Carp Cyprinus carpio

Y Cheng, P Vechtova, Z Fussy, J Sterba… - International Journal of …, 2021 - mdpi.com
The purpose of the current study was to analyze phenotypic and functional characteristics of
common carp (Cyprinus carpio) spermatozoa during in vitro aging and to investigate …

Preeclampsia promotes autism in offspring via maternal inflammation and fetal NFκB signaling

X Liu, H Liu, N Gu, J Pei, X Lin… - Life Science …, 2023 - life-science-alliance.org
Preeclampsia (PE) is a risk factor for autism spectrum disorder (ASD) in offspring. However,
the exact mechanisms underlying the impact of PE on progeny ASD are not fully understood …

Cell therapies for autism spectrum disorder based on new pathophysiology: A review

M Nabetani, T Mukai, A Taguchi - Cell Transplantation, 2023 - journals.sagepub.com
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by difficulties in social communication, repetitive behaviors, and restricted interests, with …

4-hydroxyisoleucine mediated IGF-1/GLP-1 signalling activation prevents propionic acid-induced autism-like behavioural phenotypes and neurochemical defects in …

S Bhalla, S Mehan - Neuropeptides, 2022 - Elsevier
Autism is a neuropsychiatric disorder characterized by a neurotransmitter imbalance that
impairs neurodevelopment processes. Autism development is marked by communication …

Influence of prenatal drug exposure, maternal inflammation, and parental aging on the development of autism spectrum disorder

A Sato, H Kotajima-Murakami, M Tanaka… - Frontiers in …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) affects reciprocal social interaction and produces abnormal
repetitive, restrictive behaviors and interests. The diverse causes of ASD are divided into …