The nucleus is an essential organelle for the function of cells. It holds most of the genetic
material and plays a crucial role in the regulation of cell growth and proliferation. Since …

Drug resistance and cancer relapse represent significant therapeutic challenges after
chemotherapy or immunotherapy, and a major limiting factor for long-term cancer survival …

Targeted radionuclide therapy is a revolutionary tool for the treatment of highly spread
metastatic cancers. Most current approaches rely on the use of vectors to deliver …

Abstract UNC5 receptor family (UNC5A-D) have been identified as dependence receptors
whose functions depend on the availability of their ligand netrin-1. Through binding to netrin …

Neuroendocrine carcinomas, such as neuroendocrine prostate cancer and small-cell lung
cancer, commonly have a poor prognosis and limited therapeutic options. We report that …

Abstract Background and Aims Netrin‐1 displays protumoral properties, though the
pathological contexts and processes involved in its induction remain understudied. The liver …

Dormancy in cancer is a clinical state in which residual disease remains undetectable for a
prolonged duration. At a cellular level, rare cancer cells cease proliferation and survive …

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase (RTK) that is mutated in
approximately 10% of pediatric neuroblastoma (NB). To shed light on ALK-driven signaling …

Opposite expression and pro-or anti-cancer function of YAP and its paralog TAZ/WWTR1
stratify cancers into binary YAPon and YAPoff classes. These transcriptional coactivators are …

Immunoblotting normalization issues have been recently overcome by whole lane staining.
Herein, we are taking advantage of these recent advances and of the fluorophore status of …