Epithelial surfaces protect exposed tissues in the body against intrusion of foreign materials,
including xenobiotics, pollen and microbiota. The relative permeability of the various …

The vagina has been used as a mucosal drug delivery route for a long time. Its single
characteristics can be either limitative or advantageous when drug delivery is considered …

Vaginal drug delivery systems are often preferred for treating a variety of diseases and
conditions of the female reproductive tract (FRT), as delivery can be more targeted with less …

The vagina is a region of administration with a high contact surface to obtain local or
systemic effects. This anatomical area represents special interest for government health …

Overactive bladder (OAB) and vaginal dryness are common problems after menopause.
Oxybutynin (OXY) is an antimuscarinic agent that has been available for more than 30 years …

Chitosan/alginate complexes were prepared at different polycation/polyanion molar ratios
and freeze-dried vaginal inserts were obtained for chlorhexidine digluconate local delivery …

The main objective of this work was to design thermosensitive and mucoadhesive vaginal
hydrogels able to keep their rheological and mucoadhesive properties after dilution with …

The woman's body presents a number of unique anatomical features that can constitute
valuable routes for the administration of drugs, either for local or systemic action. These are …

Prevention strategies such as the development of microbicides are thought to be valuable in
the fight against HIV/AIDS. Despite recent achievements, there is still a long road ahead in …

The vaginal mucosa is commonly exposed to a variety of topical agents, including chemical
contraceptives, drugs for the treatment of specific pathological conditions, and pathogenic …