Macrophage autophagy is a highly anti-atherogenic process that promotes the catabolism of
cytosolic lipid droplets (LDs) to maintain cellular lipid homeostasis. Selective autophagy …

Fingolimod hydrochloride (FTY720) is a first‐in‐class of sphingosine‐1‐phosphate (S1P)
receptor modulator approved to treat multiple sclerosis by its phosphorylated form (FTY720 …

Target of rapamycin (TOR) is a serine/threonine kinase that modulates cell growth and
metabolism in response to environmental changes. Transfer RNA (tRNA) is an abundant …

Nutrient availability has a profound impact on cell fate. Upon nitrogen starvation, wild-type
fission yeast cells uncouple cell growth from cell division to generate small, round-shaped …

Quiescent cells require a continuous supply of proteins to maintain protein homeostasis. In
fission yeast, entry into quiescence is triggered by nitrogen stress, leading to the inactivation …

Nutrient fluctuations in the cellular environment promote changes in cell metabolism and
growth to adapt cell proliferation accordingly. The target of rapamycin (TOR) signalling …

Cyclins are degraded by the anaphase-promoting complex/cyclosome (APC/C)-mediated
proteasome in normal mitosis. We showed that Cdc13 (cyclin B) is also degraded by …

Translocator proteins (TSPO) are conserved membrane proteins extensively studied in
mammals, but their function is still unclear. Angiosperm TSPO are transiently induced by …

Conserved translocator proteins (TSPOs) mediate cell stress responses possibly in a cell-
type-specific manner. This work reports on the molecular function of plant TSPO and their …

In Schizosaccharomyces pombe, a general strategy for survival in response to
environmental changes is sexual differentiation, which is triggered by TORC1 inactivation …